MTAP and LYRM1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MTAP	LYRM1
Gene Name		methylthioadenosine phosphorylase	LYR motif containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome	Nucleoplasm Mitochondrion Intercellular Bridge
	Molecular Function	Phosphorylase Activity S-methyl-5-thioadenosine Phosphorylase Activity
	Biological Process	Sulfur Amino Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Purine Ribonucleoside Salvage Polyamine Metabolic Process Nicotinamide Riboside Catabolic Process L-methionine Biosynthetic Process From Methylthioadenosine Methylation Response To Testosterone Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways		Metabolism of polyamines Sulfur amino acid metabolism Methionine salvage pathway Metabolism of amino acids and derivatives
Drugs		Adenine (1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol Formycin 5\'-Deoxy-5\'-Methylthioadenosine 5\'-Deoxy-5\'-(Methylthio)-Tubercidin
Diseases
GWAS		Coronary heart disease ( 21606135) Cutaneous nevi ( 19578365) Melanoma ( 21983787)
Protein-Protein Interactions		6 interactors: CDC25A CENPH FOLH1 LYRM1 MYLIP RELB	1 interactors: MTAP
Entrez ID		4507	57149
HPRD ID		01134	14254
Ensembl ID		ENSG00000099810	ENSG00000102897
Uniprot IDs		B4DUC8 Q13126	O43325
PDB IDs		1CB0 1CG6 1K27 1SD1 1SD2 3LN5 3OZC 3OZD 3OZE
Enriched GO Terms of Interacting Partners?			Purine Ribonucleoside Salvage L-methionine Biosynthetic Process From Methylthioadenosine L-methionine Salvage Methionine Biosynthetic Process Methionine Metabolic Process Sulfur Amino Acid Biosynthetic Process Purine-containing Compound Salvage Polyamine Metabolic Process Response To Testosterone Sulfur Amino Acid Metabolic Process Cellular Biogenic Amine Metabolic Process Cellular Amino Acid Biosynthetic Process Amine Metabolic Process Purine Nucleoside Metabolic Process Alpha-amino Acid Metabolic Process Nucleoside Metabolic Process Sulfur Compound Metabolic Process Methylation Cellular Amino Acid Metabolic Process Response To Steroid Hormone Nucleobase-containing Small Molecule Metabolic Process
Tagcloud ?		9p 9p21 abilities accounts aggressiveness alanosine anchorage attributable confers hemizygous homozygous immunoexpression inactivated losses methylthioadenosine myxofibrosarcoma myxofibrosarcomas pathogenically phosphorylase portended preserved recurrently reexpressing reexpression reverted spanning umbilical unfavorable xenografts
Tagcloud (Difference) ?		9p 9p21 abilities accounts aggressiveness alanosine anchorage attributable confers hemizygous homozygous immunoexpression inactivated losses methylthioadenosine myxofibrosarcoma myxofibrosarcomas pathogenically phosphorylase portended preserved recurrently reexpressing reexpression reverted spanning umbilical unfavorable xenografts
Tagcloud (Intersection) ?