MTAP

Gene Name		methylthioadenosine phosphorylase
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Phosphorylase Activity S-methyl-5-thioadenosine Phosphorylase Activity
	Biological Process	Sulfur Amino Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Purine Ribonucleoside Salvage Polyamine Metabolic Process Nicotinamide Riboside Catabolic Process L-methionine Biosynthetic Process From Methylthioadenosine Methylation Response To Testosterone Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways		Metabolism of polyamines Sulfur amino acid metabolism Methionine salvage pathway Metabolism of amino acids and derivatives
Drugs		Adenine (1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol Formycin 5\'-Deoxy-5\'-Methylthioadenosine 5\'-Deoxy-5\'-(Methylthio)-Tubercidin
Diseases
GWAS		Coronary heart disease ( 21606135) Cutaneous nevi ( 19578365) Melanoma ( 21983787)
Protein-protein Interactions		6 interactors: CDC25A CENPH FOLH1 LYRM1 MYLIP RELB
Entrez ID		4507
HPRD ID		01134
Ensembl ID		ENSG00000099810
Uniprot IDs		B4DUC8 Q13126
PDB IDs		1CB0 1CG6 1K27 1SD1 1SD2 3LN5 3OZC 3OZD 3OZE
Enriched GO Terms of Interacting Partners?
Tagcloud ?		9p 9p21 abilities accounts aggressiveness alanosine anchorage attributable confers hemizygous homozygous immunoexpression inactivated losses methylthioadenosine myxofibrosarcoma myxofibrosarcomas pathogenically phosphorylase portended preserved recurrently reexpressing reexpression reverted spanning umbilical unfavorable xenografts