CENPH and NUF2

Number of citations of the paper that reports this interaction (PMID 15713649)
13

Data Source:
BioGRID (two hybrid)

		CENPH	NUF2
Gene Name		centromere protein H	NUF2, NDC80 kinetochore complex component
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytosol	Chromosome, Centromeric Region Condensed Chromosome Kinetochore Nucleus Cytosol Membrane Ndc80 Complex
	Molecular Function	Protein Binding Kinetochore Binding	Molecular_function Protein Binding
	Biological Process	Mitotic Cell Cycle Nucleosome Assembly CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Division
Pathways		Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CENPK KIF2C MTAP NDC80 NUF2	10 interactors: ATF3 AURKA AURKB AZGP1 CENPE CENPH DTNBP1 EXOC1 NDC80 SDCBP2
Entrez ID		64946	83540
HPRD ID		12029	10817
Ensembl ID		ENSG00000153044	ENSG00000143228
Uniprot IDs		B3KVZ3 Q9H3R5	Q9BZD4
PDB IDs			2VE7 3IZ0
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Cycle Cell Division Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Mitotic Cell Cycle Process Establishment Or Maintenance Of Cell Polarity Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Chromosome Organization Cell Cycle Process Attachment Of Mitotic Spindle Microtubules To Kinetochore Purine Ribonucleoside Salvage Organelle Organization L-methionine Biosynthetic Process From Methylthioadenosine Establishment Of Organelle Localization Microtubule Depolymerization L-methionine Salvage Attachment Of Spindle Microtubules To Kinetochore Organelle Localization Microtubule Cytoskeleton Organization Methionine Biosynthetic Process Methionine Metabolic Process Sulfur Amino Acid Biosynthetic Process Purine-containing Compound Salvage CENP-A Containing Nucleosome Assembly Mitotic Metaphase Plate Congression Polyamine Metabolic Process Metaphase Plate Congression Histone Exchange DNA Replication-independent Nucleosome Assembly Response To Testosterone Establishment Of Mitotic Spindle Orientation Microtubule Polymerization Or Depolymerization Mitotic Spindle Organization Sulfur Amino Acid Metabolic Process Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Chromosome Localization Microtubule-based Process Centromere Complex Assembly Spindle Localization Microtubule Anchoring ATP-dependent Chromatin Remodeling Regulation Of Chromosome Segregation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II	Attachment Of Spindle Microtubules To Kinetochore Mitotic Spindle Organization Spindle Stabilization Attachment Of Mitotic Spindle Microtubules To Kinetochore Microtubule Anchoring Mitotic Nuclear Division Mitotic Cell Cycle Microtubule-based Process Cellular Localization Histone-serine Phosphorylation Spindle Organization Organelle Localization Cell Division Microtubule Cytoskeleton Organization Maintenance Of Protein Location In Cell Maintenance Of Protein Location Organelle Assembly Chromosome Organization Kinetochore Assembly Maintenance Of Location In Cell Protein Localization Cytoskeleton Organization Organelle Organization Kinetochore Organization Histone Phosphorylation Negative Regulation Of Microtubule Depolymerization Chromosome Segregation Cell Cycle Mitotic Cell Cycle Process Regulation Of Cell Division Centromere Complex Assembly Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Cytokinesis Negative Regulation Of Protein Binding Establishment Of Organelle Localization Cellular Protein Complex Assembly Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Spindle Checkpoint Mitotic Sister Chromatid Segregation Spindle Assembly Protein Complex Assembly Sister Chromatid Segregation Cell Cycle Process Negative Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Negative Regulation Of Binding Spindle Assembly Involved In Female Meiosis I Regulation Of Cell Cycle Process Regulation Of Protein Depolymerization
Tagcloud ?		angptl2 bik blast blasts candidate causative commercial cytopenia dysplasia epigenetic excess focusing gstm5 hypermethylation mapped methylated methylation modalities multilineage networks pairs preleukemic promoters raeb rcmd refractory rerg silencing transforms	ams2 ams2p bioinformatics cenpa centromere centromeres centromeric cnp1 cnp1p defining disrupted gata identifies incorporation kinetochore linker mal2 microarrays mis12 mis18 nucleosome nucleosomes participating pombe positioned positioning regularly schizosaccharomyces tiling
Tagcloud (Difference) ?		angptl2 bik blast blasts candidate causative commercial cytopenia dysplasia epigenetic excess focusing gstm5 hypermethylation mapped methylated methylation modalities multilineage networks pairs preleukemic promoters raeb rcmd refractory rerg silencing transforms	ams2 ams2p bioinformatics cenpa centromere centromeres centromeric cnp1 cnp1p defining disrupted gata identifies incorporation kinetochore linker mal2 microarrays mis12 mis18 nucleosome nucleosomes participating pombe positioned positioning regularly schizosaccharomyces tiling
Tagcloud (Intersection) ?