MSH4 and VBP1

Number of citations of the paper that reports this interaction (PMID 12591739)
16

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		MSH4	VBP1
Gene Name		mutS homolog 4	von Hippel-Lindau binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Synaptonemal Complex Nucleus Mismatch Repair Complex	Nucleus Cytoplasm Prefoldin Complex Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding Damaged DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Mismatched DNA Binding	Protein Binding
	Biological Process	Meiotic Mismatch Repair Ovarian Follicle Development Reciprocal Meiotic Recombination Spermatogenesis Female Gamete Generation Homologous Chromosome Segregation Chiasma Assembly	Protein Folding Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding
Pathways		Meiotic recombination	Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: MLH1 MLH3 MSH5 RPA1 VBP1	9 interactors: MKNK2 MSH4 PFDN2 PFDN4 PIK3R3 PNMA1 UBL7 VHL XRCC6
Entrez ID		4438	7411
HPRD ID		03658	02135
Ensembl ID		ENSG00000057468	ENSG00000155959
Uniprot IDs		O15457	B4DWR3 F5H2A7 P61758
PDB IDs
Enriched GO Terms of Interacting Partners?		Mismatch Repair Meiotic Nuclear Division Meiotic Cell Cycle Reciprocal Meiotic Recombination DNA Recombination Synapsis Homologous Chromosome Segregation Meiotic Chromosome Segregation Meiosis I DNA Repair Cellular Response To DNA Damage Stimulus Chromosome Segregation Chromosome Organization Reproduction Cell Cycle Process DNA Metabolic Process Cell Cycle Male Meiosis Cellular Response To Stress Cellular Component Assembly Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Double-strand Break Repair Negative Regulation Of Mitotic Recombination Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation DNA Recombinase Assembly Organelle Organization Chiasma Assembly Spindle Midzone Assembly Response To Stress Female Meiosis I Resolution Of Meiotic Recombination Intermediates Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Aromatic Compound Catabolic Process Nucleotide-excision Repair, DNA Gap Filling Nucleotide-excision Repair, DNA Damage Removal Telomere Maintenance Via Semi-conservative Replication Synaptonemal Complex Assembly Double-strand Break Repair Via Nonhomologous End Joining Chromosome Separation Negative Regulation Of DNA Recombination Synaptonemal Complex Organization Nuclear DNA Replication Telomere Maintenance Via Recombination Nuclear-transcribed MRNA Poly(A) Tail Shortening Isotype Switching Nucleobase-containing Compound Metabolic Process Mitotic Recombination	'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding
Tagcloud ?		2480delg 2480t 286c anaplastic astrocytomas codon contributed exceptionally exome fraumeni germline glioblastomas gliomas i827n inherited lats1 li missense mutational neurofibroma nf2 r827kfs r96w schwannoma schwannomas schwannomatosis sporadic stop tp53	atpase break coexist dsb e3 hek293t hippel hmsh4 homologous immunocomplex joining ligase lindau meiotic mitotic muts nonhomologous p97 partner polyubiquitination prefoldin proteolysis recombination recombinational repair strand ubiquitination vhl von
Tagcloud (Difference) ?		2480delg 2480t 286c anaplastic astrocytomas codon contributed exceptionally exome fraumeni germline glioblastomas gliomas i827n inherited lats1 li missense mutational neurofibroma nf2 r827kfs r96w schwannoma schwannomas schwannomatosis sporadic stop tp53	atpase break coexist dsb e3 hek293t hippel hmsh4 homologous immunocomplex joining ligase lindau meiotic mitotic muts nonhomologous p97 partner polyubiquitination prefoldin proteolysis recombination recombinational repair strand ubiquitination vhl von
Tagcloud (Intersection) ?