TACSTD2 and KRTAP5-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TACSTD2	KRTAP5-2
Description		tumor associated calcium signal transducer 2	keratin associated protein 5-2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Plasma Membrane Basal Plasma Membrane Membrane Lateral Plasma Membrane Extracellular Exosome	Cytosol Intermediate Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Visual Perception Negative Regulation Of Epithelial Cell Migration Regulation Of Epithelial Cell Proliferation Negative Regulation Of Stress Fiber Assembly Ureteric Bud Morphogenesis Negative Regulation Of Branching Involved In Ureteric Bud Morphogenesis Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Ruffle Assembly Negative Regulation Of Cell Motility Positive Regulation Of Stem Cell Differentiation
Pathways			Keratinization
Drugs		Sacituzumab govitecan	Beta-D-Glucose Pidolic acid
Diseases		Gelatinous drop-like corneal dystrophy (GDCD); Subepithelial amyloidosis; Primary familial amyloidosis
GWAS		Nickel levels ( 26025379)
Interacting Genes		3 interacting genes: KRTAP1-3 KRTAP10-8 KRTAP5-2	61 interacting genes: ADAMTSL4 AP4M1 CRCT1 CREB5 CRY2 DHRS1 DLGAP3 EMC7 FAM76B FUCA2 HOXA1 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LMNTD2 MACO1 MEOX2 MT1B NUFIP2 OPCML SLC13A5 SMCP TACSTD2 UBE2I
Entrez ID		4070	440021
HPRD ID		00672	17249
Ensembl ID		ENSG00000184292	ENSG00000205867
Uniprot IDs		P09758	Q701N4
PDB IDs		2MAE 2MVK 2MVL 7E5M 7E5N 7PEE
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Leading Edge Cell Differentiation Cellular Response To Anisomycin Response To Anisomycin Release From Viral Latency Transcription Factor AP-1 Complex	Intermediate Filament Keratinization Epidermis Development Keratin Filament Tissue Development Hair Cycle Protein Binding Identical Protein Binding
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