ACER1

Description		alkaline ceramidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides N-acylsphingosine Amidohydrolase Activity Metal Ion Binding
	Biological Process	Lipid Metabolic Process Sphingolipid Metabolic Process Ceramide Metabolic Process Epidermis Development Response To Alkaline PH Regulation Of Lipid Metabolic Process Sphingolipid Biosynthetic Process Sphingolipid Catabolic Process Cell Differentiation Keratinocyte Differentiation Sphingosine Biosynthetic Process Ceramide Catabolic Process Sebaceous Gland Development Cellular Response To Calcium Ion
Pathways		Sphingolipid catabolism
Drugs
Diseases
GWAS		Diffusing capacity of carbon monoxide ( 30694715)
Novel Interacting Genes		1 novel interacting genes: TMIGD2
Interacting Genes		1 interacting genes: MPP1
Entrez ID		125981
HPRD ID		12496
Ensembl ID		ENSG00000167769
Uniprot IDs		Q8TDN7
PDB IDs
Enriched GO Terms of Interacting Partners?		GMP Kinase Activity GDP Metabolic Process Stereocilium Regulation Of Neutrophil Chemotaxis Cortical Cytoskeleton GMP Metabolic Process Regulation Of Neutrophil Migration Positive Regulation Of Activated T Cell Proliferation T Cell Costimulation Regulation Of Activated T Cell Proliferation Regulation Of Granulocyte Chemotaxis
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