MITF and PATZ1

Number of citations of the paper that reports this interaction (PMID 11751862)
5

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		MITF	PATZ1
Gene Name		microphthalmia-associated transcription factor	POZ (BTB) and AT hook containing zinc finger 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Protein Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Chromatin Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Dimerization Activity	DNA Binding Chromatin Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Protein Complex Assembly Osteoclast Differentiation Melanocyte Differentiation Regulation Of Cell Proliferation Camera-type Eye Development Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Cell Fate Commitment Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Bone Remodeling	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Spermatogenesis Male Gonad Development T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: APP CTNNB1 EBP EP300 FOS GSK3B HINT1 HK3 LEF1 MAPK1 MAPK14 MARK3 OTX2 PATZ1 PAX3 PAX6 PIAS1 PIAS2 PIAS3 PSMD14 RPS6KA1 SPI1 STUB1 SUMO1 TFE3 TFEB TFEC UBE2I	6 interactors: BACH1 BACH2 MITF PRKAR1A RNF4 TP53
Entrez ID		4286	23598
HPRD ID		01138	05522
Ensembl ID		ENSG00000187098	ENSG00000100105
Uniprot IDs		B4DNC7 O75030 Q8WYR3	Q9HBE1
PDB IDs			2EPP 2EPQ 2EPR 2EPS 2YT9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Immune System Process RNA Metabolic Process Nitrogen Compound Metabolic Process Protein Sumoylation Regulation Of Metabolic Process Apoptotic Process Peptidyl-lysine Modification Programmed Cell Death Immune Response Regulation Of Cellular Protein Metabolic Process Cell Death Death Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process Peptidyl-amino Acid Modification Cellular Macromolecule Biosynthetic Process Regulation Of Cell Differentiation Macromolecule Biosynthetic Process Cellular Protein Modification Process Negative Regulation Of Biosynthetic Process Innate Immune Response Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Myeloid Cell Differentiation Biosynthetic Process Regulation Of Immune System Process Organ Development Negative Regulation Of Transcription, DNA-templated	Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Oxygen Levels Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Macromitophagy Regulation Of Kinetochore Assembly Oligodendrocyte Apoptotic Process Double-strand Break Repair DNA Damage Checkpoint Negative Regulation Of Helicase Activity Regulation Of Centromere Complex Assembly Gastrulation Regulation Of Metabolic Process Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Chromosome Organization Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Mitochondrial DNA Repair
Tagcloud ?		agricultural ammonium b16 coloring cosmetic cosmetics downregulate dyes f10 follicles hair hypopigmenting industry lawsone melanin melanogenesis melanoma microphthalmia modern mushroom permanent persulfate products proved resorcinol semi sodium temporary tyrosinase	anaplastic anchorage behaviors carcinogenesis carcinomas cytoplasm debated dedifferentiated delocalized differentiated ectopic emerging fact finger histotype increasingly insights invasiveness inverse mesenchymal oncogene opposing papillary poz proceeding restoration suppressor thyroid undifferentiated
Tagcloud (Difference) ?		agricultural ammonium b16 coloring cosmetic cosmetics downregulate dyes f10 follicles hair hypopigmenting industry lawsone melanin melanogenesis melanoma microphthalmia modern mushroom permanent persulfate products proved resorcinol semi sodium temporary tyrosinase	anaplastic anchorage behaviors carcinogenesis carcinomas cytoplasm debated dedifferentiated delocalized differentiated ectopic emerging fact finger histotype increasingly insights invasiveness inverse mesenchymal oncogene opposing papillary poz proceeding restoration suppressor thyroid undifferentiated
Tagcloud (Intersection) ?