MGST1 and NELFB

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		MGST1	NELFB
Gene Name		microsomal glutathione S-transferase 1	negative elongation factor complex member B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Apical Part Of Cell	Nucleoplasm Cytoplasm NELF Complex
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Protein Homodimerization Activity Glutathione Binding	Protein Binding
	Biological Process	Glutathione Metabolic Process Xenobiotic Metabolic Process Response To Organonitrogen Compound Response To Lipopolysaccharide Leydig Cell Differentiation Response To Drug Small Molecule Metabolic Process Oxidation-reduction Process Protein Homotrimerization Cellular Response To Lipid Hydroperoxide Glutathione Derivative Biosynthetic Process	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Aflatoxin activation and detoxification Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective ACY1 causes encephalopathy Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Visceral fat ( 22589738)
Protein-Protein Interactions		2 interactors: LTC4S NELFB	12 interactors: BRCA1 CEBPE DENR ESR1 FOS HSPA9 JUN KHDRBS3 MAPK6 MGST1 NELFA NELFE
Entrez ID		4257	25920
HPRD ID		00705	10845
Ensembl ID		ENSG00000008394	ENSG00000188986
Uniprot IDs		P10620	Q8WX92
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipoxin Metabolic Process Lipoxygenase Pathway	Positive Regulation Of Viral Transcription Response To Lipid Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Viral Transcription Biosynthetic Process Positive Regulation Of Viral Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Response To Lipopolysaccharide Negative Regulation Of DNA-templated Transcription, Elongation Response To Molecule Of Bacterial Origin Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Regulation Of Viral Process Response To Bacterium Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription Elongation From RNA Polymerase II Promoter MAPK Cascade Nitrogen Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription, DNA-templated Cellular Response To Calcium Ion Negative Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of RNA Biosynthetic Process Response To Other Organism Toll-like Receptor 5 Signaling Pathway Signal Transduction By Phosphorylation RNA Metabolic Process Toll-like Receptor 10 Signaling Pathway Regulation Of RNA Metabolic Process SMAD Protein Signal Transduction Response To Biotic Stimulus Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Nucleobase-containing Compound Metabolic Process Toll-like Receptor 9 Signaling Pathway Transcription Elongation From RNA Polymerase II Promoter
Tagcloud ?		analyse arsenate arsenic asenic carboxymethylenebutenolidase cmbl disturbed elusive etc ferrintin frh3 hub ingenity inorganic medaka metalloid microsomal million nr2f2 ontology pollutant sage slc40a1 solute tags tpm transcriptome transcripts zebrafish
Tagcloud (Difference) ?		analyse arsenate arsenic asenic carboxymethylenebutenolidase cmbl disturbed elusive etc ferrintin frh3 hub ingenity inorganic medaka metalloid microsomal million nr2f2 ontology pollutant sage slc40a1 solute tags tpm transcriptome transcripts zebrafish
Tagcloud (Intersection) ?