NELFB and DENR

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		NELFB	DENR
Gene Name		negative elongation factor complex member B	density-regulated protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm NELF Complex	Cellular_component
	Molecular Function	Protein Binding	Molecular_function Translation Initiation Factor Activity Protein Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription	Formation Of Translation Preinitiation Complex IRES-dependent Translational Initiation Ribosome Disassembly
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: BRCA1 CEBPE DENR ESR1 FOS HSPA9 JUN KHDRBS3 MAPK6 MGST1 NELFA NELFE	3 interactors: MCTS1 NELFB UBC
Entrez ID		25920	8562
HPRD ID		10845	05182
Ensembl ID		ENSG00000188986	ENSG00000139726
Uniprot IDs		Q8WX92	O43583
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Transcription Response To Lipid Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Viral Transcription Biosynthetic Process Positive Regulation Of Viral Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Response To Lipopolysaccharide Negative Regulation Of DNA-templated Transcription, Elongation Response To Molecule Of Bacterial Origin Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Regulation Of Viral Process Response To Bacterium Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription Elongation From RNA Polymerase II Promoter MAPK Cascade Nitrogen Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription, DNA-templated Cellular Response To Calcium Ion Negative Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of RNA Biosynthetic Process Response To Other Organism Toll-like Receptor 5 Signaling Pathway Signal Transduction By Phosphorylation RNA Metabolic Process Toll-like Receptor 10 Signaling Pathway Regulation Of RNA Metabolic Process SMAD Protein Signal Transduction Response To Biotic Stimulus Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Nucleobase-containing Compound Metabolic Process Toll-like Receptor 9 Signaling Pathway Transcription Elongation From RNA Polymerase II Promoter	IRES-dependent Translational Initiation Cap-independent Translational Initiation Ribosome Disassembly Transcription, DNA-templated RNA Biosynthetic Process Cytoplasmic Translational Initiation Viral Protein Processing Viral Process Cytoplasmic Translation RNA Metabolic Process Formation Of Translation Preinitiation Complex Notch Receptor Processing Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Gene Expression Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Glycogen Biosynthetic Process Intracellular Transport Of Virus Cellular Macromolecule Biosynthetic Process Cellular Response To DNA Damage Stimulus Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Organelle Disassembly Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Negative Regulation Of Type I Interferon Production Positive Regulation Of Viral Transcription Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of RNA Biosynthetic Process Toll-like Receptor 5 Signaling Pathway Regulation Of RNA Metabolic Process Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway
Tagcloud ?			40s 60s 80s abce1 augs bidirectionally codons directionality eef2 eif1 eif1a eif3 eif4f erf1 erf1erf3 imposition ligatin mct migrated posttermination puromycin recapitulated recycled reinitiate reinitiation ribosomes trna trnai unstructured
Tagcloud (Difference) ?			40s 60s 80s abce1 augs bidirectionally codons directionality eef2 eif1 eif1a eif3 eif4f erf1 erf1erf3 imposition ligatin mct migrated posttermination puromycin recapitulated recycled reinitiate reinitiation ribosomes trna trnai unstructured
Tagcloud (Intersection) ?