MGST1

Gene Name		microsomal glutathione S-transferase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Apical Part Of Cell
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Protein Homodimerization Activity Glutathione Binding
	Biological Process	Glutathione Metabolic Process Xenobiotic Metabolic Process Response To Organonitrogen Compound Response To Lipopolysaccharide Leydig Cell Differentiation Response To Drug Small Molecule Metabolic Process Oxidation-reduction Process Protein Homotrimerization Cellular Response To Lipid Hydroperoxide Glutathione Derivative Biosynthetic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Aflatoxin activation and detoxification Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective ACY1 causes encephalopathy Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS		Visceral fat ( 22589738)
Protein-protein Interactions		2 interactors: LTC4S NELFB
Entrez ID		4257
HPRD ID		00705
Ensembl ID		ENSG00000008394
Uniprot IDs		P10620
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipoxin Metabolic Process Lipoxygenase Pathway
Tagcloud ?		analyse arsenate arsenic asenic carboxymethylenebutenolidase cmbl disturbed elusive etc ferrintin frh3 hub ingenity inorganic medaka metalloid microsomal million nr2f2 ontology pollutant sage slc40a1 solute tags tpm transcriptome transcripts zebrafish