SMCP and CGB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMCP	CGB3
Description		sperm mitochondria associated cysteine rich protein	chorionic gonadotropin subunit beta 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Membrane Mitochondrial Membrane	Extracellular Region Extracellular Space Cytoplasm Pituitary Gonadotropin Complex
	Molecular Function	Protein Binding	Signaling Receptor Binding Hormone Activity Protein Binding
	Biological Process	Single Fertilization Penetration Of Zona Pellucida Flagellated Sperm Motility	Apoptotic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Female Gamete Generation Hormone-mediated Signaling Pathway
Pathways			Glycoprotein hormones TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		78 interacting genes: ALPP C14orf119 CALCOCO2 CGB3 CGB5 CGB8 CTAG2 CYSRT1 DYNLL1 DYNLL2 GOLGA2 GRN GUCD1 HOXA1 IGFBP6 KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2C LCE2D LCE3A LCE3B LCE4A LCE5A MACO1 MT1B MT1M NBPF19 NOTCH2NLA PCSK5 PLEKHG4 PLSCR1 PLSCR3 PPP1R27 PRDX5 RGS17 SLC39A7 SPRY1 TCF4 TRIM42 UBL5 VASN	7 interacting genes: APP CFTR CGA FSHB LHCGR NLGN3 SMCP
Entrez ID		4184	1082
HPRD ID		03093	00343
Ensembl ID		ENSG00000163206	ENSG00000104827
Uniprot IDs		P49901 Q5T7P5	A0A0F7RQP8 P0DN86
PDB IDs			1HCN 1HRP 1QFW 7FIG 7FIH 7FII
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Epidermis Development Keratinization Hair Cycle Tissue Development Identical Protein Binding Cytosol Lead Ion Binding Mercury Ion Binding Intracellular Zinc Ion Homeostasis	Follicle-stimulating Hormone Activity Follicle-stimulating Hormone Complex Ovulation Cycle Process Follicle-stimulating Hormone Signaling Pathway Reproductive Process Regulation Of Steroid Biosynthetic Process Regulation Of Steroid Metabolic Process Regulation Of Hormone Levels Regulation Of Lipid Biosynthetic Process Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Biological Quality Positive Regulation Of Steroid Biosynthetic Process Rhythmic Process Positive Regulation Of Steroid Metabolic Process G Protein-coupled Receptor Signaling Pathway Ovarian Follicle Development Modulation Of Excitatory Postsynaptic Potential Cognition Cellular Response To CAMP Developmental Process Involved In Reproduction Regulation Of Lipid Metabolic Process Amyloid-beta Complex Developmental Growth Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Choriogonadotropin Hormone Binding Choriogonadotropin Hormone Receptor Activity Luteinizing Hormone Receptor Activity Steroid Biosynthetic Process Regulation Of Membrane Potential Response To CAMP Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Developmental Process Golgi Lumen Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
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