SMCP and PPP1R27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMCP	PPP1R27
Description		sperm mitochondria associated cysteine rich protein	protein phosphatase 1 regulatory subunit 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Phosphatase Inhibitor Activity Protein Binding Phosphatase Binding
	Biological Process	Single Fertilization Penetration Of Zona Pellucida Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		78 interacting genes: ALPP C14orf119 CALCOCO2 CGB3 CGB5 CGB8 CTAG2 CYSRT1 DYNLL1 DYNLL2 GOLGA2 GRN GUCD1 HOXA1 IGFBP6 KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2C LCE2D LCE3A LCE3B LCE4A LCE5A MACO1 MT1B MT1M NBPF19 NOTCH2NLA PCSK5 PLEKHG4 PLSCR1 PLSCR3 PPP1R27 PRDX5 RGS17 SLC39A7 SPRY1 TCF4 TRIM42 UBL5 VASN	9 interacting genes: DDIT4L GCC1 KRT34 MVB12A NTAQ1 PPP1CA PPP1CB RPL9 SMCP
Entrez ID		4184	116729
HPRD ID		03093	17334
Ensembl ID		ENSG00000163206	ENSG00000182676
Uniprot IDs		P49901 Q5T7P5	Q86WC6
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Epidermis Development Keratinization Hair Cycle Tissue Development Identical Protein Binding Cytosol Lead Ion Binding Mercury Ion Binding Intracellular Zinc Ion Homeostasis	PTW/PP1 Phosphatase Complex Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Circadian Regulation Of Gene Expression Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process Myosin-light-chain-phosphatase Activity Protein-N-terminal Glutamine Amidohydrolase Activity Phosphatase Activity Protein Dephosphorylation RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein-N-terminal Asparagine Amidohydrolase Activity Virus Maturation Regulation Of Circadian Rhythm Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Positive Regulation Of Termination Of DNA-templated Transcription Dephosphorylation Positive Regulation Of Termination Of RNA Polymerase II Transcription Circadian Rhythm Myosin Phosphatase Activity Phosphoprotein Phosphatase Activity Glycogen Granule RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process Energy Derivation By Oxidation Of Organic Compounds Chromosome, Telomeric Region Golgi Trans Cisterna Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Cytoplasm Double-strand Break Repair Via Alternative Nonhomologous End Joining Penetration Of Zona Pellucida Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cytosol ESCRT I Complex
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