CGB3 and NLGN3

Number of citations of the paper that reports this interaction (PubMedID 25464930)
0

Data Source:
BioGRID (two hybrid)

		CGB3	NLGN3
Description		chorionic gonadotropin subunit beta 3	neuroligin 3
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Pituitary Gonadotropin Complex	Plasma Membrane Cell Surface Membrane Endocytic Vesicle Synapse Postsynaptic Membrane Excitatory Synapse Presynapse Symmetric, GABA-ergic, Inhibitory Synapse Neuron To Neuron Synapse Asymmetric, Glutamatergic, Excitatory Synapse
	Molecular Function	Signaling Receptor Binding Hormone Activity Protein Binding	Protein Binding Signaling Receptor Activity Neurexin Family Protein Binding Cell Adhesion Molecule Binding Scaffold Protein Binding
	Biological Process	Apoptotic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Female Gamete Generation Hormone-mediated Signaling Pathway	Regulation Of Respiratory Gaseous Exchange By Nervous System Process Receptor-mediated Endocytosis Cell Adhesion Neuron Cell-cell Adhesion Chemical Synaptic Transmission Synapse Assembly Learning Adult Behavior Social Behavior Synaptic Vesicle Endocytosis Axon Extension Modulation Of Chemical Synaptic Transmission Synapse Organization Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Rhythmic Synaptic Transmission Inhibitory Postsynaptic Potential Vocalization Behavior Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly Positive Regulation Of Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		Glycoprotein hormones TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Prostate cancer ( 25217961)
Interacting Genes		7 interacting genes: APP CFTR CGA FSHB LHCGR NLGN3 SMCP	65 interacting genes: AKT1 ALPP AP2A2 APC2 ATF4 ATXN1 C1orf122 C1QA CCAR2 CGB3 COBL CTSD DLG2 DLG3 DLG4 DPEP2 EBPL EFEMP1 EFS FANCG FBLN1 FHOD1 FKBP1A FLNA GDF15 GUK1 HID1 HIVEP1 ITPRIP LGALS1 MAN2C1 MAP1S MEOX2 MIEN1 NFATC4 NRDC NRXN1 NRXN2 NRXN3 OAZ1 OR1F12P PICK1 PKIB PLB1 PLCB4 PRDX2 PSAP PSG1 PSG11 PSG3 PSG4 PSG5 QARS1 RBFOX2 SPAG5 SPINT1 SSR4 TDRD7 TLE5 TNNT3 TRIM33 TXNIP UBQLN1 UBXN6 UQCRC1
Entrez ID		1082	54413
HPRD ID		00343	02275
Ensembl ID		ENSG00000104827	ENSG00000196338
Uniprot IDs		A0A0F7RQP8 P0DN86	A0A8I5KSB7 A0A8I5QJH8 B7Z3P8 Q4G160 Q9NZ94 X5D2P6 X5D7L6 X5DNV3
PDB IDs		1HCN 1HRP 1QFW 7FIG 7FIH 7FII	8GS3
Enriched GO Terms of Interacting Partners?		Follicle-stimulating Hormone Activity Follicle-stimulating Hormone Complex Ovulation Cycle Process Follicle-stimulating Hormone Signaling Pathway Reproductive Process Regulation Of Steroid Biosynthetic Process Regulation Of Steroid Metabolic Process Regulation Of Hormone Levels Regulation Of Lipid Biosynthetic Process Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Biological Quality Positive Regulation Of Steroid Biosynthetic Process Rhythmic Process Positive Regulation Of Steroid Metabolic Process G Protein-coupled Receptor Signaling Pathway Ovarian Follicle Development Modulation Of Excitatory Postsynaptic Potential Cognition Cellular Response To CAMP Developmental Process Involved In Reproduction Regulation Of Lipid Metabolic Process Amyloid-beta Complex Developmental Growth Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Choriogonadotropin Hormone Binding Choriogonadotropin Hormone Receptor Activity Luteinizing Hormone Receptor Activity Steroid Biosynthetic Process Regulation Of Membrane Potential Response To CAMP Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Developmental Process Golgi Lumen Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway	Receptor Clustering Neuroligin Family Protein Binding Kinase Binding Protein Localization To Cell Junction Vocalization Behavior Social Behavior Protein Localization To Synapse Female Pregnancy Protein Localization To Membrane Cell-cell Adhesion Neuron Cell-cell Adhesion Receptor Localization To Synapse Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Cellular Response To Metal Ion Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Apoptotic Signaling Pathway GDF15-GFRAL Signaling Pathway Somite Specification Gephyrin Clustering Involved In Postsynaptic Density Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Localization Within Membrane Ionotropic Glutamate Receptor Binding NMDA Selective Glutamate Receptor Signaling Pathway Trans-synaptic Protein Complex Postsynaptic Density Protein 95 Clustering Negative Regulation Of Signal Transduction Neuromuscular Junction Postsynapse Response To Metal Ion Negative Regulation Of Apoptotic Signaling Pathway Postsynaptic Membrane Assembly Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Learning Vocal Learning Cell Adhesion Cell-cell Signaling GMP Kinase Activity Postsynaptic Membrane Organization Neurotransmitter Secretion Observational Learning Cellular Localization Learning Or Memory Protein Kinase Inhibitor Activity Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signaling Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway PERK-mediated Unfolded Protein Response GDP Metabolic Process
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