MSANTD3 and TMEM129

Number of citations of the paper that reports this interaction (PubMedID 24412244)
0

Data Source:
BioGRID (two hybrid)

		MSANTD3	TMEM129
Description		Myb/SANT DNA binding domain containing 3	transmembrane protein 129, E3 ubiquitin ligase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Response To Unfolded Protein Protein Ubiquitination Retrograde Protein Transport, ER To Cytosol ERAD Pathway
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Conjunctival UV autofluorescence (CUVAF) ( 25590795)	Bladder cancer ( 20972438 24163127) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Type 1 diabetes ( 33830302) Urinary bladder cancer ( 20348956) Walking pace ( 33128006)
Interacting Genes		16 interacting genes: BMPR1A BUB1 CDH1 FXR1 FXR2 GNAS MCC MLH3 MUTYH PFN2 SMAD4 SUV39H1 TMEM129 TSC1 VSTM2A ZDHHC17	6 interacting genes: DLC1 MSANTD3 PDGFRL PSMD4 UBE2D1 UBE2D3
Entrez ID		91283	92305
HPRD ID		14459	14290
Ensembl ID		ENSG00000066697	ENSG00000168936
Uniprot IDs		Q96H12	A0AVI4
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To BMP Stimulus Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Presynaptic Modulation Of Chemical Synaptic Transmission Mesendoderm Development Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Multicellular Organismal Process Postsynapse Modulation Of Chemical Synaptic Transmission Cardiac Conduction System Development Negative Regulation Of Epithelial Cell Migration Translation Regulator Activity Animal Organ Development Regulation Of Growth Regulation Of Developmental Growth Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Regulation Of Cell Communication Regulation Of Signaling Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Locomotion Outflow Tract Septum Morphogenesis Regulation Of Neurogenesis Mismatch Repair Positive Regulation Of Cellular Component Organization Pituitary Gland Development Endoderm Development Regulation Of Multicellular Organismal Process Regulation Of Neural Crest Cell Differentiation Regulation Of Cellular Component Organization Regulation Of Cellular Senescence Ventricular Septum Morphogenesis Regulation Of Cell Development Regulation Of Developmental Process SMAD Binding Ventricular Cardiac Muscle Tissue Morphogenesis Neural Plate Mediolateral Regionalization Paraxial Mesoderm Structural Organization Positive Regulation Of Cell Differentiation Fibrous Ring Of Heart Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Regulation Of Nervous System Development Positive Regulation Of Cardiac Ventricle Development Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Histone H2A Kinase Activity Lamellipodium Cardiocyte Differentiation Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis	Ubiquitin Conjugating Enzyme Activity Platelet-derived Growth Factor Beta-receptor Activity Platelet-derived Growth Factor Receptor Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of BMP Signaling Pathway Protein K48-linked Ubiquitination Regulation Of BMP Signaling Pathway Hindbrain Morphogenesis Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Catabolic Process Platelet Activating Factor Receptor Activity Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ubiquitin-protein Transferase Activity Macromolecule Catabolic Process Proteasome Regulatory Particle, Base Subcomplex Protein Polyubiquitination Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
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