GABRR2

Description		gamma-aminobutyric acid type A receptor subunit rho2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Chloride Channel Complex Synapse Postsynaptic Membrane Intracellular Vesicle GABA-ergic Synapse GABA-A Receptor Complex
	Molecular Function	Transmembrane Signaling Receptor Activity GABA-A Receptor Activity Monoatomic Ion Channel Activity Extracellular Ligand-gated Monoatomic Ion Channel Activity Chloride Channel Activity Protein Domain Specific Binding GABA-gated Chloride Ion Channel Activity Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Monoatomic Ion Transport Chloride Transport Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Visual Perception Monoatomic Ion Transmembrane Transport Synaptic Transmission, GABAergic Regulation Of Postsynaptic Membrane Potential Chloride Transmembrane Transport
Pathways		GABA receptor activation
Drugs		Fludiazepam TPMPA
Diseases
GWAS		Systemic lupus erythematosus ( 32771030) Third ventricle volume ( 31530798)
Interacting Genes		5 interacting genes: CSNK2A1 GABRR1 MAP1B PRKCA SQSTM1
Entrez ID		2570
HPRD ID		15922
Ensembl ID		ENSG00000111886
Uniprot IDs		B4DER2 P28476
PDB IDs
Enriched GO Terms of Interacting Partners?		Aggrephagy Protein Targeting To Vacuole Involved In Autophagy Regulation Of Biological Quality Protein Targeting To Vacuole Protein-containing Complex Binding Protein Catabolic Process Protein Localization To Vacuole Establishment Of Protein Localization To Vacuole Regulation Of Cell Communication Regulation Of Signaling PML Body Negative Regulation Of Protein Metabolic Process Glutamatergic Synapse Modulation Of Chemical Synaptic Transmission Response To Estradiol Induction Of Synaptic Plasticity By Chemical Substance Response To Toxic Substance Positive Regulation Of Dense Core Granule Biogenesis Histone H3T6 Kinase Activity Brown Fat Cell Proliferation Amphisome Positive Regulation Of Cell Growth Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Macroautophagy Regulation Of Synapse Assembly Axonogenesis Hippocampal Mossy Fiber Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Angiotensin-activated Signaling Pathway Alphav-beta3 Integrin-PKCalpha Complex Vacuolar Transport Positive Regulation Of Autophagy Negative Regulation Of Translation Protein Kinase C Signaling Cell Death Apoptotic Process Protein Targeting Negative Regulation Of Programmed Cell Death Positive Regulation Of Aggrephagy Programmed Cell Death Synapse Response To Mechanical Stimulus Regulation Of Synaptic Plasticity Basal Dendrite Regulation Of Angiotensin-activated Signaling Pathway Cellular Component Assembly GABA Receptor Activity Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Lewy Body
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