MAOB and NFYB

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		MAOB	NFYB
Description		monoamine oxidase B	nuclear transcription factor Y subunit beta
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Membrane	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Primary Methylamine Oxidase Activity Electron Transfer Activity Oxidoreductase Activity Flavin Adenine Dinucleotide Binding Monoamine Oxidase Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity DNA-binding Transcription Factor Binding
	Biological Process	Substantia Nigra Development Dopamine Catabolic Process Hydrogen Peroxide Biosynthetic Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor
Pathways		Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB	PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs		Amphetamine Amphetamine Phentermine Procaine Tranylcypromine Phenelzine Zonisamide Selegiline Pioglitazone Procarbazine Moclobemide Moclobemide Isocarboxazid Ephedra sinica root Rasagiline MMDA 4-Methoxyamphetamine Metamfetamine Pargyline Isatin (R)-N-methyl-N-2-propynyl-1-indanamine Farnesol N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate Flavin adenine dinucleotide N-Propargyl-1(S)-Aminoindan Dodecyldimethylamine N-oxide 5-Hydroxy-N-Propargyl-1(R)-Aminoindan N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE Nialamide Nomifensine Zimelidine Safinamide 7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE 7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE (1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE 4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN (S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] Viloxazine Flortaucipir F-18 Vafidemstat
Diseases
GWAS			Toenail selenium levels ( 25343990)
Interacting Genes		6 interacting genes: COX20 FGF14 NFYB RHBDD2 SRPK1 TRIM54	26 interacting genes: AGTRAP C1QBP CEBPZ CIITA CNTN2 DRAP1 ELF1 EP300 GRB2 MAOB MEOX2 MYC NFYA NFYC POLE4 POU3F2 SMYD3 SP1 TAF11 TAF12 TAF6 TBP TP53 TP73 YBX1 YBX3
Entrez ID		4129	4801
HPRD ID		02401	01794
Ensembl ID		ENSG00000069535	ENSG00000120837
Uniprot IDs		B7Z242 P27338	F8VSL3 P25208
PDB IDs		1GOS 1OJ9 1OJA 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C70 2C72 2C73 2C75 2C76 2V5Z 2V60 2V61 2VRL 2VRM 2VZ2 2XCG 2XFN 2XFO 2XFP 2XFQ 2XFU 3PO7 3ZYX 4A79 4A7A 4CRT 5MRL 6FVZ 6FW0 6FWC 6RKB 6RKP 6RLE 6YT2 7B0V 7B0Z 7P4F 7P4H 7ZW3 9FJT	1N1J 4AWL 4CSR 6QMP 6QMQ 6QMS 7AH8 8QU2 8QU3 8QU4
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process DNA Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation RNA Polymerase II General Transcription Initiation Factor Activity Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-templated Transcription Transcription By RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Nucleoplasm CCAAT-binding Factor Complex MRNA Transcription Regulation Of Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Transcription Factor TFIID Complex DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin DNA-binding Transcription Factor Binding Nucleus Nucleobase-containing Compound Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Activity Protein-DNA Complex Protein Heterodimerization Activity MRNA Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter RNA Polymerase II Preinitiation Complex Assembly Regulation Of Cellular Response To Stress Transcription Preinitiation Complex Assembly Transcription Cis-regulatory Region Binding Host-mediated Activation Of Viral Transcription Nucleic Acid Metabolic Process
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