ANKRD45

Description		ankyrin repeat domain 45
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Plasma Membrane Midbody Cleavage Furrow Flemming Body
	Molecular Function	Molecular_function Protein Binding
	Biological Process	Cell Population Proliferation
Pathways
Drugs
Diseases
GWAS		Feeling tense ( 29500382) General cognitive ability ( 29844566) Mosquito bite size ( 28199695) Neurociticism ( 29500382)
Interacting Genes		5 interacting genes: APP LHX3 MAGEA2 MAGEA2B TRIM54
Entrez ID		339416
HPRD ID		13501
Ensembl ID		ENSG00000183831
Uniprot IDs		Q5TZF3
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Acetylation Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Sumoylation Regulation Of Ubiquitin-protein Transferase Activity Cellular Senescence Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Post-translational Protein Modification Signal Transduction By P53 Class Mediator Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Ubiquitination Histone Deacetylase Binding PML Body Medial Motor Column Neuron Differentiation Prolactin Secreting Cell Differentiation PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling DNA-binding Transcription Factor Binding Ventral Spinal Cord Interneuron Specification Somatotropin Secreting Cell Differentiation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Protein Ubiquitination Regulation Of Spontaneous Synaptic Transmission Negative Regulation Of Transcription By RNA Polymerase II NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity
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