ASIC1 and STOM

Number of citations of the paper that reports this interaction (PMID 15471860)
26

Data Source:
HPRD (in vivo)

		ASIC1	STOM
Gene Name		acid sensing (proton gated) ion channel 1	stomatin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Space Cytoplasm Cytoskeleton Integral Component Of Plasma Membrane Membrane Vesicle Melanosome Membrane Raft Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Protein Binding Ligand-gated Sodium Channel Activity Acid-sensing Ion Channel Activity	Protein Homodimerization Activity
	Biological Process	Transport Sodium Ion Transport Calcium Ion Transport Signal Transduction Response To PH Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sensory Perception Of Sour Taste Transmembrane Transport Protein Homotrimerization Cellular Response To PH	Protein Homooligomerization Regulation Of Acid-sensing Ion Channel Activity
Pathways		Ion channel transport Stimuli-sensing channels
Drugs		Diclofenac Amiloride
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ASIC2 ATXN3 PICK1 PRKACA STOM	9 interactors: ASIC1 ASIC2 ASIC3 DVL3 LANCL1 RPL13A RUVBL1 RUVBL2 SLC2A1
Entrez ID		41	2040
HPRD ID		04182	00585
Ensembl ID		ENSG00000110881	ENSG00000148175
Uniprot IDs		A8K1U5 P78348	P27105
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cation Channel Activity Synaptic Transmission Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cell-cell Signaling Response To Abiotic Stimulus Regulation Of Ion Transmembrane Transport Phototransduction Regulation Of Blood Coagulation Regulation Of Ion Transport Detection Of Light Stimulus Regulation Of Systemic Arterial Blood Pressure By Aortic Arch Baroreceptor Feedback Positive Regulation Of Dense Core Granule Biogenesis Regulation Of Acid-sensing Ion Channel Activity Positive Regulation Of Transport Regulation Of Wound Healing Cell Maturation Histone H3-T6 Phosphorylation Nervous System Development Detection Of Abiotic Stimulus Sensory Perception Of Sour Taste Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning DNA Methylation Involved In Embryo Development Cellular Response To Acidic PH Regulation Of Synaptic Transmission Positive Regulation Of Cellular Component Biogenesis Desmosome Assembly Monoubiquitinated Protein Deubiquitination Dendritic Spine Maintenance Negative Regulation Of Glial Cell Apoptotic Process Response To Light Stimulus Regulation Of Tight Junction Assembly Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Neuronal Ion Channel Clustering Cell Communication By Electrical Coupling Involved In Cardiac Conduction Calcium-mediated Signaling Using Intracellular Calcium Source Desmosome Organization Response To Parathyroid Hormone Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Protein Export From Nucleus Misfolded Or Incompletely Synthesized Protein Catabolic Process Negative Regulation Of Actin Nucleation Cell Communication By Electrical Coupling Cellular Response To Misfolded Protein Cellular Response To PH	Sensory Perception Of Sour Taste Response To PH Sensory Perception Of Taste Cellular Response To Stimulus Histone H2A Acetylation Cellular Response To PH Response To Acidic PH Response To Abiotic Stimulus Sodium Ion Transmembrane Transport Response To Stimulus Detection Of Mechanical Stimulus Involved In Sensory Perception Sodium Ion Transport Detection Of Mechanical Stimulus Histone H4 Acetylation DNA Duplex Unwinding DNA Geometric Change Enterobactin Transport Negative Regulation Of Formation Of Translation Preinitiation Complex Regulation Of Systemic Arterial Blood Pressure By Aortic Arch Baroreceptor Feedback Sensory Perception Of Chemical Stimulus Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Siderophore Transport Negative Regulation Of Estrogen Receptor Binding Transcriptional Activation By Promoter-enhancer Looping Protein Acetylation Dehydroascorbic Acid Transport Monovalent Inorganic Cation Transport Non-canonical Wnt Signaling Pathway Via JNK Cascade Detection Of Abiotic Stimulus Sensory Perception Of Mechanical Stimulus Regulation Of Cellular Process Chromatin Remodeling Xenobiotic Transport Non-canonical Wnt Signaling Pathway Via MAPK Cascade Establishment Of Protein Localization To Chromatin Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Transmembrane Transport Sensory Perception Ion Transport Cellular Response To Acidic PH Negative Regulation Of Receptor Binding Response To Mechanical Stimulus Metal Ion Transport DNA Recombination Peptidyl-lysine Modification Cation Transmembrane Transport
Tagcloud ?		amiloride asic2a asic3 asics blocker currents cyclooxygenase defense elusive exact existed existence glia homomeric lipopolysaccharide meanwhile microglia microglial neuroinflammatory nonspecific participate pctx1 qpcr scavenger scrape sensing transcriptase
Tagcloud (Difference) ?		amiloride asic2a asic3 asics blocker currents cyclooxygenase defense elusive exact existed existence glia homomeric lipopolysaccharide meanwhile microglia microglial neuroinflammatory nonspecific participate pctx1 qpcr scavenger scrape sensing transcriptase
Tagcloud (Intersection) ?