STOM and CRAT

		STOM	CRAT
Description		stomatin	carnitine O-acetyltransferase
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Cytoskeleton Plasma Membrane Membrane Cytoplasmic Vesicle Vesicle Azurophil Granule Membrane Specific Granule Membrane Melanosome Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Membrane Blood Microparticle	Mitochondrion Mitochondrial Inner Membrane Peroxisome Peroxisomal Matrix Endoplasmic Reticulum Cytosol Membrane
	Molecular Function	Protein Binding Ion Channel Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity RNA Polymerase Binding	Acyl-CoA Oxidase Activity Carnitine O-acetyltransferase Activity Carnitine O-octanoyltransferase Activity Transferase Activity Acyltransferase Activity
	Biological Process	Regulation Of Monoatomic Ion Transmembrane Transport Host-mediated Activation Of Viral Genome Replication Positive Regulation Of Viral Process Positive Regulation Of Protein Targeting To Membrane	Lipid Metabolic Process Fatty Acid Metabolic Process Carnitine Metabolic Process, CoA-linked Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Short-chain Fatty Acid Metabolic Process Medium-chain Fatty Acid Metabolic Process
Pathways		Stimuli-sensing channels Neutrophil degranulation RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOJ GTPase cycle	Beta-oxidation of pristanoyl-CoA Peroxisomal protein import Peroxisomal protein import
Drugs			Levocarnitine Coenzyme A (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium
Diseases		Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS			Blood metabolite levels ( 26401656) Hypersomnia (HLA-DQB1*06:02 negative) ( 30266950) Meat-related diet ( 32066663) Pelvic organ prolapse (moderate/severe) ( 26545240) Red blood cell count ( 32888494) Red cell distribution width ( 27863252 28957414) Serum metabolite levels ( 33031748)
Interacting Genes		81 interacting genes: AIG1 APOA2 ASIC1 ASIC2 ASIC3 ATP1B3 ATP6V0B ATP6V0C BCL2L2 BNIP1 C2 C3orf52 CFHR5 CHST1 CLDN19 CLRN2 CMTM5 CNIH3 CTXN3 CYB5B CYB5R3 DAGLA DVL3 EMP1 ERG28 FAXDC2 FUNDC2 GIMAP1 GIMAP5 GPR25 GPR37L1 GRM2 HMOX2 KCNK1 KTN1 LANCL1 LNPEP MGLL MMP14 NKG7 ORMDL1 PEDS1-UBE2V1 PEMT PGA4 PMP22 PTCH1 RPL13A RPRM RTP2 RUVBL1 RUVBL2 SCD SELENOK SERP2 SFT2D1 SFT2D2 SFXN1 SFXN5 SLC2A1 SLC35B4 SMCO4 STX6 TECR THSD7B TMEM109 TMEM120B TMEM140 TMEM14B TMEM203 TMEM208 TMEM254 TMEM60 TMEM86B TMEM98 TMPO TNF TNFRSF10C TSPO2 VAMP4 WFDC2 YIPF6
Entrez ID		2040	1384
HPRD ID		00585	08971
Ensembl ID		ENSG00000148175	ENSG00000095321
Uniprot IDs		F8VSL7 P27105	A0A7P0TAR1 H0Y4Z7 P43155
PDB IDs		7WH3	1NM8 1S5O
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Sensory Perception Of Sour Taste Endoplasmic Reticulum Response To Acidic PH Sodium Channel Activity PH-gated Sodium Channel Activity Monoatomic Ion-gated Channel Activity Ligand-gated Sodium Channel Activity Protein Binding Cellular Response To Type II Interferon Response To PH PH-gated Monoatomic Ion Channel Activity Nitric-oxide Synthase Complex Synaptic Vesicle To Endosome Fusion Mitochondrial Outer Membrane Response To Type II Interferon Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Nitrite Reductase (NO-forming) Activity R2TP Complex Cellular Response To PH Detection Of Mechanical Stimulus Involved In Sensory Perception Acylglycerol Catabolic Process Diacylglycerol Catabolic Process Lipid Biosynthetic Process Amino Acid Transport Organic Anion Transport Telomerase RNA Localization To Cajal Body Sensory Perception Of Taste Response To Mechanical Stimulus Plasma Membrane	Host-mediated Perturbation Of Viral Genome Replication Host-mediated Activation Of Viral Genome Replication Ion Channel Inhibitor Activity RNA Polymerase Binding Positive Regulation Of Protein Targeting To Membrane Regulation Of Protein Targeting To Membrane Host-mediated Activation Of Viral Process Tertiary Granule Membrane Azurophil Granule Membrane Specific Granule Membrane Host-mediated Perturbation Of Viral Process Positive Regulation Of Viral Process Melanosome Modulation Of Process Of Another Organism Blood Microparticle Host-mediated Perturbation Of Symbiont Process Regulation Of Viral Process Vesicle Membrane Raft Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Establishment Of Protein Localization
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