SMAD3 and HDAC1

  • Number of citations of the paper that reports this interaction (PMID 10575014)
  • 59
  • Data Source:
  • BioGRID (pull down, genetic interference)

SMAD3

HDAC1

Gene Name SMAD family member 3 histone deacetylase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 268 interactors: AATF ACTB AES AKT1 ANAPC10 ANK3 APMAP APOB APP AR ARHGEF6 ATF2 ATF3 AXIN1 AXIN2 BLZF1 BPTF BRCA1 BRCA2 BTRC C10orf54 CAMK2G CCDC33 CDC16 CDC25A CDC27 CDK2 CDK4 CDK8 CDK9 CEBPA CEBPB CEBPD CFDP1 CFH CFLAR CHRD CLASRP CORO1A CPSF7 CPTP CREBBP CSH2 CSNK1D CSNK1G2 CTCF CTNNB1 CUL1 CXXC5 CYP11A1 DAB2 DACH1 DDX5 DEDD DNAJB4 DVL1 E2F4 E2F5 EBI3 EID2 EIF4ENIF1 EP300 EPAS1 EPB41 ERBB2IP ESR1 ESR2 ETS1 FBLN1 FHL2 FHL3 FLI1 FLNA FOS FOXG1 FOXH1 FOXO1 FOXO3 FOXO4 GGA1 GIT2 GLI3 GMEB1 GSC GSK3B GTF2IRD1 HDAC1 HDAC4 HDAC5 HEY1 HEYL HGS HIPK2 HIVEP1 HMGA2 HNF4A HNRNPK HOXC11 HP HSPA4 IL37 ISL1 ITCH JPH3 JUN JUNB JUND KANSL1 KAT2B KDM2A KMT2B KPNB1 KRT10 KRT2 LBP LCK LEF1 LMNA MAGI2 MAP3K7 MAPK1 MAPK14 MAPK8 MAPK9 MAX MBD1 MCM3AP MDM4 MECOM MED15 MEN1 MEOX2 MTF2 MYC MYD88 MYO5B MYOCD MYOD1 NCOA6 NEDD4 NEDD4L NEDD9 NF1 NFYC NOTCH1 NOTCH4 NR3C1 NR4A1 NUP153 NUP214 OTUB1 PAEP PAPPA PARD3 PARD3B PARP4 PAX8 PCDH1 PCK2 PEX6 PHC2 PIAS2 PIAS3 PIAS4 PIK3CA PIN1 PLAG1 PLAGL1 PLG PML PPM1A PPP1R12C PPP2R1A PRDM4 PRKAR1B PRKAR2A PROX1 PRTN3 PSMD11 RAB38 RANBP9 RARG RASD2 RASL12 RBL1 RBX1 RCVRN RELA RIOK2 RIT1 RNF111 RNF31 RPA1 RPLP0 RRAS2 RUNX2 RUNX3 S100A4 SAP130 SERTAD1 SETD2 SF3A1 SF3B2 SIN3A SKI SKIL SKOR2 SMAD1 SMAD2 SMAD4 SMAD9 SMURF1 SMURF2 SNRNP70 SNW1 SP1 SPTBN1 SQSTM1 SREBF2 SRY SS18L1 ST6GALNAC2 STRAP STUB1 SVEP1 TANK TDP2 TEKT4 TF TFE3 TGFBR1 TGFBR2 TGIF1 TGIF2 TGM2 TLR4 TMED1 TOB1 TP53 TP73 TPM3 TSC2 TSC22D4 UBQLN4 UCHL5 USP15 USP7 VDR VIM WEE1 WWP1 WWP2 XRCC6 YBX1 YY1 ZBTB16 ZBTB3 ZC3H12A ZCCHC14 ZDHHC4 ZEB1 ZEB2 ZFYVE9 ZMYM2 ZMYND11 ZNF329 ZNF8 ZNF83 193 interactors: APEX1 APPL1 AR ARHGAP35 ARID4A ATF3 ATRX BAZ2A BCL3 BCL6B BCOR BHLHE40 BRCA1 BRMS1 BRMS1L BUB1 BUB1B BUB3 CBFA2T3 CDC20 CDH1 CDKN1A CDYL CHD1 CHD4 CHFR CIITA CNTN2 CREBBP CREM CSNK2A1 CSNK2A2 CTBP1 DAXX DDB2 DDX17 DHX30 DNMT1 DNMT3A DNMT3B DNMT3L EED EID2 EID2B ELK1 ENO1 EP300 EZH2 FKBP3 FOXG1 FRA10F GATAD2A GATAD2B GCM1 GMNN GPS2 HBP1 HDAC2 HDAC3 HDAC7 HDAC9 HELLS HEY2 HIC1 HIF1A HIF1AN HIST1H4A HIST3H3 HNRNPD HR HUS1 IKZF1 ING1 IRF5 JDP2 KAT5 KCTD11 KDM1A KLF1 KLF11 KLF4 KLF5 LCOR LINC00152 MAD1L1 MAGEA1 MBD2 MBD3 MBD3L2 MBD4 MCM6 MDM2 MECOM MECP2 MEN1 MIER1 MORF4L2 MTA1 MXD1 MYOD1 NCOR2 NFE4 NFKB1 NFKBIA NKX2-5 NKX3-2 NR1D2 NR2E3 NR2F2 NRIP1 NUP98 PARP1 PCNA PEX14 PHB PHB2 PHF12 PHF21A PIAS3 PIAS4 PIK3R1 PITX2 PLK4 PML PPARD PPARG PPP2R1B PRKACA PRKG1 PRRG4 PTMA RAD9A RAP1A RARA RB1 RBBP4 RBBP7 RBL1 RBL2 RBP1 RBPJ RELA REPIN1 RFC1 RFC4 RICTOR RUNX1 RUNX1T1 RUNX3 RUVBL1 RUVBL2 SALL1 SAP18 SAP30 SATB1 SATB2 SENP1 SET SETDB1 SIN3A SIN3B SMAD2 SMAD3 SOX6 SP1 SP3 SPEN SPI1 STAT2 STAT3 SUDS3 SUV39H1 SYK TAB2 TAL1 TFCP2 TGIF1 TGIF2 THAP11 TOP2A TOP2B TP53 TPD52L1 TRIM27 TXNIP UBE2I UHRF2 VHL VPRBP WISP2 ZBTB16 ZMYND11 ZNF76
Entrez ID 4088 3065
HPRD ID 04380 03143
Ensembl ID ENSG00000166949 ENSG00000116478
Uniprot IDs P84022 Q9P0T0 Q13547 Q6IT96
PDB IDs 1MHD 1MJS 1MK2 1OZJ 1U7F 2LAJ 2LB2 1TYI 4BKX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenoviral  autoinhibitory  cdk  coactivators  competing  conformational  constructs  creb  define  e1a  effector  facilitating  fragment  interacting  modulates  oncoprotein  p15  p300  participate  possibility  potentiates  removes  smad4  smads  squelching  tgf  transactivation  transduce 
bhlh  complexes  corepressors  deacetylase  deacetylation  heterodimerize  heterodimers  heterogeneous  immunocomplexes  mad  max  mediates  members  msin3a  msin3b  multimeric  multiprotein  p50  p55  polypeptides  possess  reporter  repress  repression  ternary  tightly  transcriptional  trapoxin  zip 
Tagcloud (Difference) ?
adenoviral  autoinhibitory  cdk  coactivators  competing  conformational  constructs  creb  define  e1a  effector  facilitating  fragment  interacting  modulates  oncoprotein  p15  p300  participate  possibility  potentiates  removes  smad4  smads  squelching  tgf  transactivation  transduce 
bhlh  complexes  corepressors  deacetylase  deacetylation  heterodimerize  heterodimers  heterogeneous  immunocomplexes  mad  max  mediates  members  msin3a  msin3b  multimeric  multiprotein  p50  p55  polypeptides  possess  reporter  repress  repression  ternary  tightly  transcriptional  trapoxin  zip 
Tagcloud (Intersection) ?