RTCA and MIR19B2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		RTCA	MIR19B2
Description		RNA 3'-terminal phosphate cyclase	microRNA 19b-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	RISC Complex
	Molecular Function	Nucleotide Binding RNA Binding Catalytic Activity RNA-3'-phosphate Cyclase Activity Protein Binding ATP Binding Ligase Activity
	Biological Process	RNA Processing Negative Regulation Of Optical Nerve Axon Regeneration	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways
Drugs
Diseases
GWAS
Interacting Genes		49 interacting genes: MIR1-1 MIR106B MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR199A1 MIR199A2 MIR19B2 MIR200A MIR205 MIR20B MIR21 MIR214 MIR222 MIR25 MIR29B2 MIR29C MIR31 MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-2 MIR92A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEIL3 OTX2	93 interacting genes: ADARB1 AIMP1 AIMP2 AQR C1QBP CELF1 CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PATL1 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RBMS2 RTCA RTCB SART3 SF1 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2B TRIM25 U2SURP UPF1 USP36 UTP20 YBX1 YBX3 ZFR ZNF346 ZNF385A
Entrez ID		8634	406981
HPRD ID		15280
Ensembl ID		ENSG00000137996	ENSG00000284107
Uniprot IDs		O00442
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Extracellular Vesicle Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Metabolic Process Regulation Of Anatomical Structure Morphogenesis Extracellular Space Negative Regulation Of Cytokine Production Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Tissue Remodeling Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Translation Negative Regulation Of Cell Motility Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Locomotion MRNA Destabilization Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Connective Tissue Replacement Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis RNA Destabilization Regulation Of Endothelial Cell Migration Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Developmental Process Regulation Of Cell Migration Regulation Of Multicellular Organismal Development Regulation Of Cell Motility Positive Regulation Of MRNA Metabolic Process	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process MRNA Binding Nucleobase-containing Compound Metabolic Process Nucleus MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex Spliceosomal Complex MRNA 3'-UTR Binding Catalytic Step 2 Spliceosome Regulation Of Translation MiRNA Binding Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Translation Regulation Of Gene Expression Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity RNA Stabilization TRNA Aminoacylation Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Stability MRNA Stabilization Ligase Activity Regulation Of RNA Stability Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Nucleolus Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Helicase Activity Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cytoplasmic Translation
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