ZC3H7B and MIR16-2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		ZC3H7B	MIR16-2
Description		zinc finger CCCH-type containing 7B	microRNA 16-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Space RISC Complex
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Metal Ion Binding
	Biological Process	Post-transcriptional Regulation Of Gene Expression MiRNA Processing	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body size at age 10 ( 32376654) Caffeine consumption from tea ( 33287642) Eosinophil count ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) General factor of neuroticism ( 30867560) Lamb consumption ( 32066663) Lymphocyte count ( 32888494) Meat-related diet ( 32066663) Medication use (thyroid preparations) ( 31015401) Neuroticism ( 29255261) Neutrophil percentage of granulocytes ( 27863252) Refractive error ( 32231278) Schizophrenia ( 29483656 28991256) Smoking cessation ( 33082346) Sum eosinophil basophil counts ( 27863252) Vitiligo ( 27723757) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Bipolar disorder ( 31043756) Malaria ( 31844061)
Interacting Genes		6 interacting genes: ATXN1 ATXN1L MIR16-2 MIR205 MIR29A MIR7-1	83 interacting genes: ADARB1 APOBEC3B ATXN2L C1QBP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBMS1 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 UPF1 UTP20 YBX1 YBX2 YBX3 ZC3H7A ZC3H7B ZFR ZNF346
Entrez ID		23264	406951
HPRD ID		06711
Ensembl ID		ENSG00000100403	ENSG00000198987
Uniprot IDs		Q9UGR2
PDB IDs
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing POZ Domain Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Lung Alveolus Development Social Behavior MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA Base-pairing Post-transcriptional Repressor Activity FMN Transmembrane Transporter Activity FAD Transmembrane Transporter Activity FAD Transmembrane Transport Negative Regulation Of Gene Expression AMP Transport AMP Transmembrane Transporter Activity Memory Coenzyme A Transmembrane Transport Coenzyme A Transmembrane Transporter Activity NAD Transmembrane Transport ADP Transmembrane Transporter Activity NAD Transmembrane Transporter Activity Negative Regulation Of Vasculature Development MRNA 3'-UTR Binding Negative Regulation Of Angiogenesis Negative Regulation Of Circulating Fibrinogen Levels Adenine Nucleotide Transmembrane Transporter Activity NAD Transport Regulation Of Aorta Morphogenesis Negative Regulation Of Fibroblast Growth Factor Production Regulation Of Endothelial Cell Proliferation Learning Regulation Of Gene Expression Regulation Of Cell Population Proliferation Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of Endothelial Cell Migration Fatty Acid Alpha-oxidation Poly(G) Binding ATP Transmembrane Transporter Activity Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Artery Morphogenesis Brain Development Positive Regulation Of Extracellular Matrix Disassembly	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process MRNA Processing RNA Splicing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Nucleus Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Post-transcriptional Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Nucleoplasm Spliceosomal Complex Cytoplasmic Stress Granule MiRNA Binding MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Catalytic Step 2 Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Negative Regulation Of MRNA Catabolic Process Negative Regulation Of Translation RNA Stabilization Regulation Of Macromolecule Biosynthetic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Ligase Activity TRNA Aminoacylation Regulation Of Macromolecule Metabolic Process MRNA Stabilization Positive Regulation Of Cytoplasmic Translation Regulation Of Primary Metabolic Process CRD-mediated MRNA Stabilization Regulation Of Metabolic Process MRNA 5'-UTR Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process TRNA Metabolic Process
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