MCCD1 and KRT26

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MCCD1	KRT26
Description		mitochondrial coiled-coil domain 1	keratin 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process		Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		AIDS progression ( 19115949) Asthma ( 29273806 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Cervical cancer ( 28806749) Inflammatory bowel disease ( 28067908) Lymphocyte count ( 32888494) Malaria ( 31844061) Ulcerative colitis ( 28067908)	Asthma ( 31959851) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		26 interacting genes: BEX3 BFSP2 CAB39 COX5B FNDC3B KANK2 KRT26 KYNU LMO4 LSM1 MEIS2 MGAT5B MKRN3 MX1 MYL7 P4HA3 PIH1D2 PPP1R16A PRR35 QARS1 RIPPLY1 USHBP1 USP20 ZNF417 ZNF587 ZNF765	30 interacting genes: BLOC1S2 CCDC146 FAM86C1P HGS KIFC3 KRT1 KRT3 KRT4 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 MCCD1 SLC19A1 SNAPIN SUOX TRIB3 TXLNB UCHL5 USHBP1 WASHC1
Entrez ID		401250	353288
HPRD ID		17470	17243
Ensembl ID		ENSG00000204511	ENSG00000186393
Uniprot IDs		A0A1U9X802 P59942	Q7Z3Y9
PDB IDs
Enriched GO Terms of Interacting Partners?			Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Cytosol Regulation Of Lysosome Size BORC Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane BLOC-1 Complex Anterograde Synaptic Vesicle Transport Regulation Of Vesicle Size Protein Binding Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Sulfite Oxidase Activity Positive Regulation Of Late Endosome To Lysosome Transport Gamma-tubulin Binding Synaptic Vesicle Transport Epidermis Development Melanosome Organization Pigment Granule Organization
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