KRT26 and MCCD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT26	MCCD1
Description		keratin 26	mitochondrial coiled-coil domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Mitochondrion
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31959851) Cognitive decline rate in late mild cognitive impairment ( 26252872)	AIDS progression ( 19115949) Asthma ( 29273806 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Cervical cancer ( 28806749) Inflammatory bowel disease ( 28067908) Lymphocyte count ( 32888494) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		30 interacting genes: BLOC1S2 CCDC146 FAM86C1P HGS KIFC3 KRT1 KRT3 KRT4 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 MCCD1 SLC19A1 SNAPIN SUOX TRIB3 TXLNB UCHL5 USHBP1 WASHC1	26 interacting genes: BEX3 BFSP2 CAB39 COX5B FNDC3B KANK2 KRT26 KYNU LMO4 LSM1 MEIS2 MGAT5B MKRN3 MX1 MYL7 P4HA3 PIH1D2 PPP1R16A PRR35 QARS1 RIPPLY1 USHBP1 USP20 ZNF417 ZNF587 ZNF765
Entrez ID		353288	401250
HPRD ID		17243	17470
Ensembl ID		ENSG00000186393	ENSG00000204511
Uniprot IDs		Q7Z3Y9	A0A1U9X802 P59942
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Cytosol Regulation Of Lysosome Size BORC Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane BLOC-1 Complex Anterograde Synaptic Vesicle Transport Regulation Of Vesicle Size Protein Binding Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Sulfite Oxidase Activity Positive Regulation Of Late Endosome To Lysosome Transport Gamma-tubulin Binding Synaptic Vesicle Transport Epidermis Development Melanosome Organization Pigment Granule Organization
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