MCCD1 and CAB39

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MCCD1	CAB39
Description		mitochondrial coiled-coil domain 1	calcium binding protein 39
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Extracellular Region Cytoplasm Cytosol Z Disc Protein-containing Complex Secretory Granule Lumen Extracellular Exosome Serine/threonine Protein Kinase Complex Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	Protein Binding Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity Protein Serine/threonine Kinase Binding
	Biological Process		Signal Transduction Response To Activity Intracellular Signal Transduction Cellular Hypotonic Response Response To Thyroid Hormone Negative Regulation Of Potassium Ion Transmembrane Transport
Pathways			Energy dependent regulation of mTOR by LKB1-AMPK Neutrophil degranulation
Drugs
Diseases
GWAS		AIDS progression ( 19115949) Asthma ( 29273806 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Cervical cancer ( 28806749) Inflammatory bowel disease ( 28067908) Lymphocyte count ( 32888494) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		26 interacting genes: BEX3 BFSP2 CAB39 COX5B FNDC3B KANK2 KRT26 KYNU LMO4 LSM1 MEIS2 MGAT5B MKRN3 MX1 MYL7 P4HA3 PIH1D2 PPP1R16A PRR35 QARS1 RIPPLY1 USHBP1 USP20 ZNF417 ZNF587 ZNF765	13 interacting genes: CEBPA CEP44 GOLGA2 IPO5 MCCD1 MED7 PRKAA1 RSL1D1 SHMT2 STK11 STK24 STRADA STRADB
Entrez ID		401250	51719
HPRD ID		17470	10091
Ensembl ID		ENSG00000204511	ENSG00000135932
Uniprot IDs		A0A1U9X802 P59942	Q9Y376
PDB IDs			1UPK 1UPL 2WTK 3GNI 4FZA 4FZD 4FZF 4NZW 4O27 8VSU
Enriched GO Terms of Interacting Partners?			Organelle Disassembly Serine/threonine Protein Kinase Complex Regulation Of Protein Metabolic Process Intracellular Protein-containing Complex Activation Of Protein Kinase Activity Negative Regulation Of Translational Initiation Negative Regulation Of Hepatocyte Apoptotic Process Protein Modification Process Positive Regulation Of Protein Metabolic Process Protein Metabolic Process Protein Kinase Activity G1 To G0 Transition Regulation Of Translational Initiation Macromolecule Metabolic Process Cadherin Binding Positive Regulation Of Phosphate Metabolic Process Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Protein Modification Process Positive Regulation Of Protein Kinase Activity Protein Phosphorylation Positive Regulation Of Kinase Activity Negative Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Protein Modification Process Phosphorylation Regulation Of Protein Localization To Nucleus Protein Export From Nucleus Regulation Of Translation Rescue Of Stalled Ribosome Intracellular Signal Transduction Negative Regulation Of Translation Protein Kinase Activator Activity Carbohydrate Homeostasis Macrophage Differentiation Glucose Homeostasis RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Dexamethasone Multicellular Organismal-level Homeostasis Centrosome Cycle Negative Regulation Of Glucosylceramide Biosynthetic Process L-allo-threonine Aldolase Activity Regulation Of Type I Interferon-mediated Signaling Pathway Ribosome Disassembly Negative Regulation Of Immune Response Response To Ketone Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Signal Transduction Positive Regulation Of Protein Phosphorylation Negative Regulation Of Immune System Process Regulation Of Protein Kinase Activity Regulation Of Immune Response
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