KRT26 and KRT4

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT26	KRT4
Description		keratin 26	keratin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Nucleus Cytosol Intermediate Filament Cell Surface Keratin Filament Intermediate Filament Cytoskeleton
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization	Cytoskeleton Organization Epithelial Cell Differentiation Keratinization Intermediate Filament Organization Negative Regulation Of Epithelial Cell Proliferation
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases			White sponge nevus
GWAS		Asthma ( 31959851) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		30 interacting genes: BLOC1S2 CCDC146 FAM86C1P HGS KIFC3 KRT1 KRT3 KRT4 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 MCCD1 SLC19A1 SNAPIN SUOX TRIB3 TXLNB UCHL5 USHBP1 WASHC1	22 interacting genes: C14orf119 CCDC57 CEP57 KIFC3 KRT14 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 PPP1R13B TRIM54 TUBGCP4
Entrez ID		353288	3851
HPRD ID		17243	00478
Ensembl ID		ENSG00000186393	ENSG00000170477
Uniprot IDs		Q7Z3Y9	P19013
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Cytosol Regulation Of Lysosome Size BORC Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane BLOC-1 Complex Anterograde Synaptic Vesicle Transport Regulation Of Vesicle Size Protein Binding Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Sulfite Oxidase Activity Positive Regulation Of Late Endosome To Lysosome Transport Gamma-tubulin Binding Synaptic Vesicle Transport Epidermis Development Melanosome Organization Pigment Granule Organization	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Organization Tissue Morphogenesis Cytoskeleton Epithelial Cell Differentiation Organelle Organization Anatomical Structure Morphogenesis Extracellular Exosome Structural Constituent Of Cytoskeleton Cell Differentiation Cellular Developmental Process Cytosol Hair Cycle Developmental Process Hair Follicle Morphogenesis Epidermis Development Hair Cycle Process Cell Periphery Microtubule Nucleation Centriolar Satellite Gamma-tubulin Binding Microtubule Intermediate Filament Polymerization Sulfite Oxidase Activity Protein Binding Intermediate Filament Polymerization Or Depolymerization Negative Regulation Of Entry Of Bacterium Into Host Cell Zonula Adherens Maintenance Terminal Web Molybdenum Ion Binding Keratinization Scaffold Protein Binding Microtubule Binding Molybdopterin Cofactor Binding
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