KRT26 and KRT6B

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT26	KRT6B
Description		keratin 26	keratin 6B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization	Ectoderm Development Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases			Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		Asthma ( 31959851) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		30 interacting genes: BLOC1S2 CCDC146 FAM86C1P HGS KIFC3 KRT1 KRT3 KRT4 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 MCCD1 SLC19A1 SNAPIN SUOX TRIB3 TXLNB UCHL5 USHBP1 WASHC1	30 interacting genes: GOLGA2 KDM1A KIFC3 KRT13 KRT15 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 LINC00839 NDC80 NUP62 OIP5 PDE4B SMARCB1 TEX11 TFIP11 TRIM54 TUBGCP4
Entrez ID		353288	3854
HPRD ID		17243	01012
Ensembl ID		ENSG00000186393	ENSG00000185479
Uniprot IDs		Q7Z3Y9	P04259
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Cytosol Regulation Of Lysosome Size BORC Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane BLOC-1 Complex Anterograde Synaptic Vesicle Transport Regulation Of Vesicle Size Protein Binding Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Sulfite Oxidase Activity Positive Regulation Of Late Endosome To Lysosome Transport Gamma-tubulin Binding Synaptic Vesicle Transport Epidermis Development Melanosome Organization Pigment Granule Organization	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Cell Differentiation Cellular Developmental Process Extracellular Exosome Structural Constituent Of Cytoskeleton Developmental Process Cytosol Hair Follicle Morphogenesis Epidermis Development Gamma-tubulin Complex Hair Cycle Meiotic Spindle Assembly Hair Cycle Process Spindle Assembly Meiotic Spindle Organization Microtubule Binding Microtubule Nucleation Membraneless Organelle Assembly Intermediate Filament Polymerization Gamma-tubulin Binding Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Kinetochore Adaptor Activity Meiotic Gene Conversion Z Disc Chromosome Segregation
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