LGALS7 and YAF2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		LGALS7	YAF2
Name		galectin 7	YY1 associated factor 2
Structure
GO Annotations	Cellular Component	None	Nucleus Nucleoplasm Cytosol
	Molecular Function	None	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	None	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription
Pathways		Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs		Beta-D-Glucose beta-D-Galactosamine	None
GWAS		Logical memory (immediate recall) in mild cognitive impairment ( 29274321 )	Refractive error ( 32231278 )
Novel Interactors		None recorded	1 novel interactors: TBK1
Interacting Genes		8 interacting genes: CA12 CDC42 HSPA6 LSM2 SSBP1 TAB1 TGM5 YAF2	28 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 PTEN SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42
Entrez ID		3963	10138
HPRD ID		09002	09606
Ensembl ID		ENSG00000205076	ENSG00000015153
Uniprot IDs		P47929	B4DJQ9 G3V212 Q8IY57
PDB IDs		1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S 6VTO 6VTP 6VTQ 6VTR 6VTS 7N4O 7N57 7N6C 7N8D 7N8G 7N96 7RDG 7TKW 7TKX 7TKY 7TKZ 7TRN 7TRO 7XAC 7XBL	2D9G
GO Terms Enriched among Interactors		None	Nucleoplasm Regulation Of MiRNA Transcription Positive Regulation Of Telomere Maintenance Protein Tag Activity Regulation Of Synaptic Vesicle Clustering Regulation Of DNA Strand Elongation Ino80 Complex Positive Regulation Of Telomere Maintenance In Response To DNA Damage Chromatin Organization Regulation Of MiRNA Metabolic Process