VPREB1

Name	V-set pre-B cell surrogate light chain 1
Structure
Interactors	3 interactors: IGHM LGALS1 VPREB3
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Immunoglobulin Complex
	Biological Process	Immune Response
Pathways	Cell surface interactions at the vascular wall
GWAS	Diastolic blood pressure ( 29208002 ) Periodontitis (PAL4Q3) ( 24024966 ) Response to selective serotonin reuptake inhibitors in depression ( 27622933 )
Entrez ID	7441
HPRD ID	05505
Ensembl ID	ENSG00000169575
Uniprot IDs	P12018
PDB IDs	2H32 2H3N 3BJ9
GO Terms Enriched among Interactors ?	Immunoglobulin Complex Hexameric IgM Immunoglobulin Complex Pentameric IgM Immunoglobulin Complex Lactose Binding Galectin Complex IgM B Cell Receptor Complex IgM Immunoglobulin Complex Pre-B Cell Allelic Exclusion Positive Regulation Of Dendritic Cell Differentiation Plasma Cell Differentiation Immune System Process Negative Regulation Of T-helper 17 Cell Lineage Commitment Immunoglobulin Receptor Binding Extracellular Region Negative Regulation Of Cell Fate Commitment Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of T-helper 17 Type Immune Response Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of Dendritic Cell Differentiation Peptidoglycan Binding Laminin Binding Regulation Of Viral Entry Into Host Cell Negative Regulation Of T-helper Cell Differentiation Positive Regulation Of Viral Life Cycle Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Mature B Cell Differentiation Involved In Immune Response Regulation Of T-helper 17 Cell Differentiation Negative Regulation Of Alpha-beta T Cell Differentiation Phosphatidylcholine Binding Myoblast Differentiation Mature B Cell Differentiation Antigen Binding Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of T-helper 17 Type Immune Response T Cell Costimulation Regulation Of Cell Fate Commitment B Cell Receptor Signaling Pathway Regulation Of Immune Response Negative Regulation Of T Cell Differentiation Regulation Of T-helper Cell Differentiation Negative Regulation Of Alpha-beta T Cell Activation Positive Regulation Of Immune System Process Antibacterial Humoral Response Negative Regulation Of Lymphocyte Differentiation Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Viral Process B Cell Activation Involved In Immune Response