LAG3 and CEBPZ

Number of citations of the paper that reports this interaction (PubMedID 11592063)
0

Data Source:
HPRD (two hybrid, in vitro)

		LAG3	CEBPZ
Description		lymphocyte activating 3	CCAAT enhancer binding protein zeta
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane	Nucleus Nucleoplasm CCAAT-binding Factor Complex
	Molecular Function	Antigen Binding Transmembrane Signaling Receptor Activity Protein Binding MHC Class II Protein Binding	DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding
	Biological Process	Adaptive Immune Response Plasmacytoid Dendritic Cell Activation Immune System Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production T Cell Activation Natural Killer Cell Mediated Cytotoxicity Innate Immune Response Negative Regulation Of Regulatory T Cell Differentiation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Negative Regulation Of T Cell Activation	Positive Regulation Of Transcription By RNA Polymerase II
Pathways		MHC class II antigen presentation
Drugs		Relatlimab
Diseases
GWAS		Blood protein levels ( 30072576)	Schizophrenia ( 23974872)
Interacting Genes		2 interacting genes: CEBPZ CPAP	18 interacting genes: CRYAA GSK3B HMOX2 LAG3 LAMTOR3 LTB4R2 LZTR1 MFHAS1 NFYB PCBD1 PRKRA RNF10 RPS6KA6 RXRG STAT6 TP53 TP73 UBE3A
Entrez ID		3902	10153
HPRD ID		01077	09875
Ensembl ID		ENSG00000089692	ENSG00000115816
Uniprot IDs		P18627	Q03701
PDB IDs		7TZG 7TZH 7UM3 8SO3 8SR0 9BF9
Enriched GO Terms of Interacting Partners?			Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II P53 Binding ER Overload Response Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Intrinsic Apoptotic Signaling Pathway MDM2/MDM4 Family Protein Binding TOR Signaling Positive Regulation Of Intracellular Signal Transduction Mitochondrion Organization Negative Regulation Of Cell Development Transcription Cis-regulatory Region Binding Regulation Of Gliogenesis Regulation Of Regulatory NcRNA Processing Signal Transduction By P53 Class Mediator Negative Regulation Of Glial Cell Proliferation Regulation Of Circadian Rhythm Signal Transduction Intracellular Signal Transduction Release Of Cytochrome C From Mitochondria Negative Regulation Of Developmental Process RNA Polymerase II Transcription Regulator Complex Response To Stress Response To Oxidative Stress Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity T Cell Lineage Commitment Protein Phosphatase 2A Binding Positive Regulation Of Apoptotic Signaling Pathway Regulation Of TOR Signaling Negative Regulation Of Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleoplasm Regulation Of Gene Expression Negative Regulation Of Catalytic Activity ER-nucleus Signaling Pathway Regulation Of Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Signal Transduction Negative Regulation Of Multicellular Organismal Process Regulation Of Microtubule Anchoring At Centrosome RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
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