CEBPZ and RXRG

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		CEBPZ	RXRG
Description		CCAAT enhancer binding protein zeta	retinoid X receptor gamma
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm CCAAT-binding Factor Complex	Chromatin Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Steroid Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Retinoic Acid-responsive Element Binding Metal Ion Binding Molecular Condensate Scaffold Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Nervous System Development Cell Differentiation Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway
Pathways			Nuclear Receptor transcription pathway Signaling by Retinoic Acid
Drugs			Adapalene Bexarotene Rosiglitazone Acitretin Alitretinoin Tretinoin Etretinate Bezafibrate Phthalic Acid Doconexent
Diseases
GWAS		Schizophrenia ( 23974872)	AIDS ( 19754311) Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder ( 27890468) Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Macular thickness ( 30535121) Menarche (age at onset) ( 21102462 25231870 27182965 29773799) Metabolite levels ( 23823483) Personality traits in bipolar disorder ( 21368711) Proportion of activated microglia (midfrontal cortex) ( 30679421) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		18 interacting genes: CRYAA GSK3B HMOX2 LAG3 LAMTOR3 LTB4R2 LZTR1 MFHAS1 NFYB PCBD1 PRKRA RNF10 RPS6KA6 RXRG STAT6 TP53 TP73 UBE3A	33 interacting genes: CAMK2B CEBPZ CHGB CKMT1A CKMT1B CREBBP DCK HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 NRIP1 PICK1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR
Entrez ID		10153	6258
HPRD ID		09875	01579
Ensembl ID		ENSG00000115816	ENSG00000143171
Uniprot IDs		Q03701	A0A087WZ88 F1D8Q7 F1T097 P48443
PDB IDs			2GL8 7A79
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II P53 Binding ER Overload Response Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Intrinsic Apoptotic Signaling Pathway MDM2/MDM4 Family Protein Binding TOR Signaling Positive Regulation Of Intracellular Signal Transduction Mitochondrion Organization Negative Regulation Of Cell Development Transcription Cis-regulatory Region Binding Regulation Of Gliogenesis Regulation Of Regulatory NcRNA Processing Signal Transduction By P53 Class Mediator Negative Regulation Of Glial Cell Proliferation Regulation Of Circadian Rhythm Signal Transduction Intracellular Signal Transduction Release Of Cytochrome C From Mitochondria Negative Regulation Of Developmental Process RNA Polymerase II Transcription Regulator Complex Response To Stress Response To Oxidative Stress Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity T Cell Lineage Commitment Protein Phosphatase 2A Binding Positive Regulation Of Apoptotic Signaling Pathway Regulation Of TOR Signaling Negative Regulation Of Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleoplasm Regulation Of Gene Expression Negative Regulation Of Catalytic Activity ER-nucleus Signaling Pathway Regulation Of Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Signal Transduction Negative Regulation Of Multicellular Organismal Process Regulation Of Microtubule Anchoring At Centrosome RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Nuclear Receptor Activity Nuclear Retinoid X Receptor Binding Intracellular Receptor Signaling Pathway RNA Polymerase II Transcription Regulator Complex Nuclear Receptor-mediated Signaling Pathway Retinoic Acid Receptor Signaling Pathway Chromatin Sequence-specific DNA Binding Hormone-mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process MRNA Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cholesterol Storage Negative Regulation Of MiRNA Transcription Negative Regulation Of RNA Metabolic Process MRNA Transcription Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MiRNA Transcription Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Chromatin DNA Binding Regulation Of RNA Biosynthetic Process Regulation Of MiRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Lipid Storage Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Ketone Metabolic Process DNA-templated Transcription Negative Regulation Of Macrophage Derived Foam Cell Differentiation DNA Binding Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Nuclear Receptor Binding Trachea Cartilage Development Regulation Of Lipid Storage
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