Wiki-Pi

  • About
  • Search
  • People
  • Updates

LAG3

Description lymphocyte activating 3
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Plasma Membrane
  • External Side Of Plasma Membrane
  • Cell Surface
  • Membrane
Molecular Function
  • Antigen Binding
  • Transmembrane Signaling Receptor Activity
  • Protein Binding
  • MHC Class II Protein Binding
Biological Process
  • Adaptive Immune Response
  • Plasmacytoid Dendritic Cell Activation
  • Immune System Process
  • Cell Surface Receptor Signaling Pathway
  • Negative Regulation Of Interleukin-2 Production
  • T Cell Activation
  • Natural Killer Cell Mediated Cytotoxicity
  • Innate Immune Response
  • Negative Regulation Of Regulatory T Cell Differentiation
  • Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
  • Regulation Of Immune Response
  • Negative Regulation Of T Cell Activation
Pathways
  • MHC class II antigen presentation
Drugs
  • Relatlimab
Diseases
GWAS
  • Blood protein levels ( 30072576)
Novel Interacting Genes 5 novel interacting genes: ALCAM CLEC4D GNAI2 KCNA1 UBE2E3
Interacting Genes 2 interacting genes: CEBPZ CPAP
Entrez ID 3902
HPRD ID 01077
Ensembl ID ENSG00000089692
Uniprot IDs P18627
PDB IDs 7TZG 7TZH 7UM3 8SO3 8SR0 9BF9
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025