LAG3

Name	lymphocyte activating 3
Structure
Novel Interactors	5 novel interactors: ALCAM CLEC4D GNAI2 KCNA1 UBE2E3
Interactors	2 interactors: CEBPZ CPAP
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Antigen Binding Transmembrane Signaling Receptor Activity Protein Binding MHC Class II Protein Binding
	Biological Process	Adaptive Immune Response Plasmacytoid Dendritic Cell Activation Immune System Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production T Cell Activation Natural Killer Cell Mediated Cytotoxicity Innate Immune Response Negative Regulation Of Regulatory T Cell Differentiation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Negative Regulation Of T Cell Activation
Pathways	MHC class II antigen presentation
Drugs	Relatlimab
GWAS	Blood protein levels ( 30072576 )
Entrez ID	3902
HPRD ID	01077
Ensembl ID	ENSG00000089692
Uniprot IDs	P18627
PDB IDs	7TZG 7TZH 7UM3 8SO3 8SR0 9BF9