REP15 and ZRSR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		REP15	ZRSR2
Description		RAB15 effector protein	zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Endosome Membrane Membrane Early Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex U2AF Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Receptor Recycling Transferrin Transport	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: ARID3A GNG11 RAB15 RAB34 RAB3A RAB3C RAB3D ZRSR2 ZRSR2P1	23 interacting genes: APP CCNL1 CLK1 CLK2 DSCR9 DVL3 KHDC4 LUC7L2 PRPF6 REP15 RPS27L SDCBP2 SPATS2L SRPK2 SRRM4 SRSF1 SRSF2 SRSF5 SSX2IP TEPSIN TNFAIP8L1 U2AF1 U2AF2
Entrez ID		387849	8233
HPRD ID		18804	02068
Ensembl ID		ENSG00000174236	ENSG00000169249
Uniprot IDs		Q6BDI9	A0A8I5KSD0 Q15696
PDB IDs		8A4A 8A4B 8A4C
Enriched GO Terms of Interacting Partners?		GTP-dependent Protein Binding GTPase Activity Myosin V Binding GTP Binding Regulation Of Exocytosis Positive Regulation Of Regulated Secretory Pathway Exocytosis Pre-mRNA 3'-splice Site Binding U2AF Complex Positive Regulation Of Exocytosis Secretion By Cell Regulation Of Regulated Secretory Pathway Synaptic Vesicle Secretion Vesicle Protein Transport Regulation Of Vesicle-mediated Transport Regulation Of Secretion By Cell Vesicle-mediated Transport Regulation Of Secretion Establishment Of Protein Localization Perinuclear Region Of Cytoplasm Lysosome Localization Positive Regulation Of Secretion By Cell Metal Ion Binding Regulation Of Presynaptic Dense Core Granule Exocytosis Positive Regulation Of Secretion Evoked Neurotransmitter Secretion Hydrolase Activity Nucleotide Binding Intracellular Protein Localization Sensory Perception Of Touch Antigen Processing And Presentation Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Regulation Of Dense Core Granule Exocytosis Zymogen Granule Clathrin-sculpted Glutamate Transport Vesicle Membrane Acrosomal Vesicle Exocytosis Clathrin-sculpted Monoamine Transport Vesicle Membrane Constitutive Secretory Pathway Cytosolic Ciliogenesis Regulation Of Plasma Membrane Repair Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Macropinocytosis Spliceosomal Complex Synaptic Vesicle Maturation Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Maintenance Of Presynaptic Active Zone Structure MRNA Splicing, Via Spliceosome Secretory Vesicle	Regulation Of RNA Splicing Nuclear Speck Protein-RNA Complex Assembly RNA Splicing MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA Metabolic Process MRNA Splice Site Recognition RNA Binding RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein-containing Complex Assembly Spliceosomal Complex Regulation Of MRNA Metabolic Process Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions MRNA Binding RS Domain Binding Positive Regulation Of RNA Splicing Pre-mRNA 3'-splice Site Binding U2AF Complex Spliceosomal Complex Assembly RNA Metabolic Process Protein Kinase B Binding Cellular Component Assembly MRNA Splicing, Via Spliceosome Nucleus Catalytic Step 2 Spliceosome U2-type Prespliceosome Protein Serine/threonine/tyrosine Kinase Activity Liver Regeneration Neuron Maturation Nucleoplasm Nucleic Acid Binding Nucleic Acid Metabolic Process Frizzled Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Glucose Transporter Complex Coated Vesicle Membrane
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