REP15 and RAB3C

Number of citations of the paper that reports this interaction (PubMedID 35871249)
67

Data Source:
BioGRID (pull down)

		REP15	RAB3C
Description		RAB15 effector protein	RAB3C, member RAS oncogene family
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GO Annotations	Cellular Component	Endosome Endosome Membrane Membrane Early Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome	Endosome Plasma Membrane Synaptic Vesicle Membrane Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding
	Biological Process	Receptor Recycling Transferrin Transport	Exocytosis Protein Transport Regulation Of Exocytosis Antigen Processing And Presentation
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS			Breast cancer ( 23535729 29059683) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Perceived intensity of sweet substances ( 31005972) Sleep duration (long sleep) ( 30846698)
Interacting Genes		9 interacting genes: ARID3A GNG11 RAB15 RAB34 RAB3A RAB3C RAB3D ZRSR2 ZRSR2P1	7 interacting genes: CRYAA FKBP2 RABIF REP15 RIMS2 RPH3AL VRTN
Entrez ID		387849	115827
HPRD ID		18804	06704
Ensembl ID		ENSG00000174236	ENSG00000152932
Uniprot IDs		Q6BDI9	Q96E17
PDB IDs		8A4A 8A4B 8A4C	6Y7G
Enriched GO Terms of Interacting Partners?		GTP-dependent Protein Binding GTPase Activity Myosin V Binding GTP Binding Regulation Of Exocytosis Positive Regulation Of Regulated Secretory Pathway Exocytosis Pre-mRNA 3'-splice Site Binding U2AF Complex Positive Regulation Of Exocytosis Secretion By Cell Regulation Of Regulated Secretory Pathway Synaptic Vesicle Secretion Vesicle Protein Transport Regulation Of Vesicle-mediated Transport Regulation Of Secretion By Cell Vesicle-mediated Transport Regulation Of Secretion Establishment Of Protein Localization Perinuclear Region Of Cytoplasm Lysosome Localization Positive Regulation Of Secretion By Cell Metal Ion Binding Regulation Of Presynaptic Dense Core Granule Exocytosis Positive Regulation Of Secretion Evoked Neurotransmitter Secretion Hydrolase Activity Nucleotide Binding Intracellular Protein Localization Sensory Perception Of Touch Antigen Processing And Presentation Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Regulation Of Dense Core Granule Exocytosis Zymogen Granule Clathrin-sculpted Glutamate Transport Vesicle Membrane Acrosomal Vesicle Exocytosis Clathrin-sculpted Monoamine Transport Vesicle Membrane Constitutive Secretory Pathway Cytosolic Ciliogenesis Regulation Of Plasma Membrane Repair Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Macropinocytosis Spliceosomal Complex Synaptic Vesicle Maturation Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Maintenance Of Presynaptic Active Zone Structure MRNA Splicing, Via Spliceosome Secretory Vesicle
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