AMIGO3 and AMIGO1

Number of citations of the paper that reports this interaction (PubMedID 12629050)
35

Data Source:
HPRD (in vitro, in vivo)

		AMIGO3	AMIGO1
Description		adhesion molecule with Ig like domain 3	adhesion molecule with Ig like domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Axon Dendrite Neuronal Cell Body Membrane Cell Projection Neuron Projection Neuronal Cell Body Perikaryon Pericellular Basket
	Molecular Function	Protein-containing Complex Binding	Protein Binding Potassium Channel Regulator Activity
	Biological Process	Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Nervous System Development Brain Development Negative Regulation Of Neuron Projection Development Positive Regulation Of Synapse Assembly	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Nervous System Development Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Cell Differentiation Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Cellular Component Organization Positive Regulation Of Nervous System Development Positive Regulation Of Synapse Assembly Neuron Projection Fasciculation Positive Regulation Of Potassium Ion Transmembrane Transport Cellular Response To L-glutamate
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Mood instability ( 31168069) Multisite chronic pain ( 31194737) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 21297633)	Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)
Interacting Genes		2 interacting genes: AMIGO1 AMIGO2	35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2
Entrez ID		386724	57463
HPRD ID		16484	11129
Ensembl ID		ENSG00000176020	ENSG00000181754
Uniprot IDs		Q86WK7	Q86WK6
PDB IDs
Enriched GO Terms of Interacting Partners?		Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Synapse Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Positive Regulation Of Cell Junction Assembly Regulation Of Synapse Assembly Regulation Of Multicellular Organismal Development Positive Regulation Of Developmental Process Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Pericellular Basket Brain Development Regulation Of Cell Junction Assembly Positive Regulation Of Nervous System Development Positive Regulation Of Multicellular Organismal Process Regulation Of Synapse Organization Cellular Response To L-glutamate Positive Regulation Of Cell Development Regulation Of Nervous System Development RSC-type Complex Cell-cell Adhesion Positive Regulation Of Cellular Component Biogenesis Regulation Of Developmental Process Regulation Of Cellular Component Organization Response To L-glutamate Axonal Fasciculation Neuron Projection Fasciculation Neuronal Cell Body Membrane Positive Regulation Of Potassium Ion Transmembrane Transport Regulation Of Nucleotide-excision Repair Regulation Of Multicellular Organismal Process Nuclear Chromosome SWI/SNF Complex Positive Regulation Of Potassium Ion Transport Regulation Of G0 To G1 Transition Regulation Of Cell Development Transcription Elongation By RNA Polymerase II Positive Regulation Of Myoblast Differentiation Positive Regulation Of Cell Differentiation Potassium Channel Regulator Activity Cell Adhesion Neuron Recognition DNA-templated Transcription Elongation	Membrane Cholesterol Binding Glutamine Transport L-glutamine Transmembrane Transporter Activity
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