CTSZ and KRTAP10-10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTSZ	KRTAP10-10
Description		cathepsin Z	keratin associated protein 10-10
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Lumen Plasma Membrane Cell Cortex Cell Surface COPII-coated ER To Golgi Transport Vesicle Growth Cone Extracellular Matrix Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Specific Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Cysteine-type Carboxypeptidase Activity	Protein Binding
	Biological Process	Angiotensin Maturation Proteolysis Negative Regulation Of Plasminogen Activation Proteolysis Involved In Protein Catabolic Process Epithelial Tube Branching Involved In Lung Morphogenesis
Pathways		Metabolism of Angiotensinogen to Angiotensins COPII-mediated vesicle transport Lysosome Vesicle Biogenesis Cargo concentration in the ER Neutrophil degranulation	Keratinization
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Heel bone mineral density x serum urate levels interaction ( 34046847) Hematocrit ( 32888494) Inflammatory bowel disease ( 23128233) Lymphocyte count ( 32888494) Mean platelet volume ( 22139419 24026423 27863252 32888494) Platelet count ( 32888494) Platelet distribution width ( 27863252 32888494)
Interacting Genes		21 interacting genes: BACH2 BANP CYSRT1 FHL5 HSF2BP KRT35 KRT40 KRTAP1-1 KRTAP10-1 KRTAP10-10 KRTAP2-3 KRTAP2-4 KRTAP3-3 KRTAP5-9 KRTAP6-3 MID2 MTUS2 NBPF19 NOTCH2NLA PLSCR1 TNS2	26 interacting genes: AXIN2 CATSPER1 CREB5 CSNK1G3 CTSZ CYSRT1 HOXA1 KRTAP10-8 KRTAP4-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-3 LCE1B LCE1C LCE1E LCE1F LCE2C LCE3B LCE3C NBPF19 NDUFB7 NOTCH2NLA PLEKHF2 ZNF473 ZNF587
Entrez ID		1522	353333
HPRD ID		04410	11185
Ensembl ID		ENSG00000101160	ENSG00000221859
Uniprot IDs		Q9UBR2	P60014
PDB IDs		1DEU 1EF7
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament	Epidermis Development Keratinization Tissue Development Intermediate Filament Identical Protein Binding Keratin Filament
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