CTSZ

Gene Name		cathepsin Z
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Gene Ontology Annotations	Cellular Component	Extracellular Space Lysosome Endoplasmic Reticulum Plasma Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Cysteine-type Peptidase Activity
	Biological Process	Angiotensin Maturation Proteolysis Cellular Protein Metabolic Process Epithelial Tube Branching Involved In Lung Morphogenesis
Pathways		Peptide hormone metabolism Metabolism of Angiotensinogen to Angiotensins trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Mean platelet volume ( 22139419)
Protein-protein Interactions		6 interactors: KRT40 KRTAP5-9 MID2 MTUS2 NOTCH2NL PLSCR1
Entrez ID		1522
HPRD ID		04410
Ensembl ID		ENSG00000101160
Uniprot IDs		Q9UBR2
PDB IDs		1DEU 1EF7
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Process Regulation Of Viral Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Phosphatidylserine Biosynthetic Process Protein Localization To Microtubule Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Phospholipid Scrambling Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Entry Into Host Cell Response To Interferon-beta Regulation Of Viral Entry Into Host Cell Protein Localization To Cytoskeleton Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Phosphatidylserine Metabolic Process Positive Regulation Of ATPase Activity Regulation Of Mast Cell Activation Acute-phase Response Regulation Of ATPase Activity See more
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