KRT6B and KRT33B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT6B	KRT33B
Description		keratin 6B	keratin 33B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Extracellular Space Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Ectoderm Development Keratinization Intermediate Filament Organization	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Cycle Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS
Interacting Genes		30 interacting genes: GOLGA2 KDM1A KIFC3 KRT13 KRT15 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 LINC00839 NDC80 NUP62 OIP5 PDE4B SMARCB1 TEX11 TFIP11 TRIM54 TUBGCP4	61 interacting genes: ABI2 AIMP2 AQP1 ARFIP1 ATG9A C1orf216 CCDC24 CNNM3 COX5B CYSRT1 DES DTNB DUSP21 FASLG FRS3 GOLGA6L2 GSTP1 HAPLN2 HDAC4 HGS HOXA1 INCA1 KDM1A KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LMO4 MOS NUP54 NUP58 PATZ1 PPP1R18 RAB26 RAMAC RTP5 RUNX1T1 SCNM1 SGF29 SHC3 USP2 VPS37C
Entrez ID		3854	3884
HPRD ID		01012	04136
Ensembl ID		ENSG00000185479	ENSG00000131738
Uniprot IDs		P04259	Q14525
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Cell Differentiation Cellular Developmental Process Extracellular Exosome Structural Constituent Of Cytoskeleton Developmental Process Cytosol Hair Follicle Morphogenesis Epidermis Development Gamma-tubulin Complex Hair Cycle Meiotic Spindle Assembly Hair Cycle Process Spindle Assembly Meiotic Spindle Organization Microtubule Binding Microtubule Nucleation Membraneless Organelle Assembly Intermediate Filament Polymerization Gamma-tubulin Binding Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Kinetochore Adaptor Activity Meiotic Gene Conversion Z Disc Chromosome Segregation	Intermediate Filament Organization Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Keratin Filament Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Protein Binding Epidermis Development Intermediate Filament Cytoskeleton Extracellular Exosome Cornified Envelope Tissue Development Developmental Process Structural Constituent Of Cytoskeleton
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