KRT6B and KRT32

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT6B	KRT32
Description		keratin 6B	keratin 32
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Ectoderm Development Keratinization Intermediate Filament Organization	Morphogenesis Of An Epithelium Epidermis Development Epithelial Cell Differentiation Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS
Interacting Genes		30 interacting genes: GOLGA2 KDM1A KIFC3 KRT13 KRT15 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 LINC00839 NDC80 NUP62 OIP5 PDE4B SMARCB1 TEX11 TFIP11 TRIM54 TUBGCP4	17 interacting genes: CCDC187 GATAD2A KIFC3 KRT2 KRT3 KRT5 KRT6B KRT72 KRT75 KRT76 KRT78 KRT8 KRT80 KRT86 NEDD9 TCHP UBASH3A
Entrez ID		3854	3882
HPRD ID		01012	04134
Ensembl ID		ENSG00000185479	ENSG00000108759
Uniprot IDs		P04259	Q14532
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Cell Differentiation Cellular Developmental Process Extracellular Exosome Structural Constituent Of Cytoskeleton Developmental Process Cytosol Hair Follicle Morphogenesis Epidermis Development Gamma-tubulin Complex Hair Cycle Meiotic Spindle Assembly Hair Cycle Process Spindle Assembly Meiotic Spindle Organization Microtubule Binding Microtubule Nucleation Membraneless Organelle Assembly Intermediate Filament Polymerization Gamma-tubulin Binding Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Kinetochore Adaptor Activity Meiotic Gene Conversion Z Disc Chromosome Segregation	Keratin Filament Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Intermediate Filament Cytoskeleton Cytosol Structural Constituent Of Cytoskeleton Epidermis Development Desmosome Intermediate Filament Polymerization Cornified Envelope Keratinocyte Activation Intermediate Filament Polymerization Or Depolymerization Positive Regulation Of Immunological Synapse Formation Scaffold Protein Binding Zonula Adherens Maintenance
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