KRT33B and KRT85

Number of citations of the paper that reports this interaction (PubMedID 40437099)
172

Data Source:
BioGRID (two hybrid, biochemical)

		KRT33B	KRT85
Description		keratin 33B	keratin 85
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Extracellular Space Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Cycle Intermediate Filament Organization	Epidermis Development Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases			Ectodermal dysplasia, pure hair-nail type (HNED)
GWAS			Body mass index ( 28552196)
Interacting Genes		61 interacting genes: ABI2 AIMP2 AQP1 ARFIP1 ATG9A C1orf216 CCDC24 CNNM3 COX5B CYSRT1 DES DTNB DUSP21 FASLG FRS3 GOLGA6L2 GSTP1 HAPLN2 HDAC4 HGS HOXA1 INCA1 KDM1A KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LMO4 MOS NUP54 NUP58 PATZ1 PPP1R18 RAB26 RAMAC RTP5 RUNX1T1 SCNM1 SGF29 SHC3 USP2 VPS37C	27 interacting genes: ALOX12 CLIC3 CREB5 CYSRT1 GNE HAPLN2 KLHL38 KRT13 KRT14 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT39 KRT40 LHX8 OTX1 TAB2 ZNF655
Entrez ID		3884	3891
HPRD ID		04136	04139
Ensembl ID		ENSG00000131738	ENSG00000135443
Uniprot IDs		Q14525	B7Z7N3 F5GYI5 P78386
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Keratin Filament Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Protein Binding Epidermis Development Intermediate Filament Cytoskeleton Extracellular Exosome Cornified Envelope Tissue Development Developmental Process Structural Constituent Of Cytoskeleton	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Organization Anatomical Structure Morphogenesis Cytoskeleton Extracellular Exosome Epidermis Development Cell Differentiation Hair Cycle Cellular Developmental Process Developmental Process Organelle Organization Structural Constituent Of Cytoskeleton Establishment Of Skin Barrier Skin Epidermis Development Cytosol Tissue Development Cornified Envelope Hair Follicle Morphogenesis Hepoxilin-epoxide Hydrolase Activity Lipoxin B4 Biosynthetic Process Protein Binding Diencephalon Morphogenesis N-acetylglucosamine Biosynthetic Process UDP-N-acetylglucosamine 2-epimerase Activity Leukotriene A4 Metabolic Process Lipoxin B4 Metabolic Process Linoleate 13S-lipoxygenase Activity Arachidonate 15-lipoxygenase Activity Lipoxin A4 Biosynthetic Process Intermediate Filament Cytoskeleton Protein-disulfide Reductase (glutathione) Activity N-acylmannosamine Kinase Activity N-acetylneuraminate Biosynthetic Process Lipoxin Biosynthetic Process Lipoxin A4 Metabolic Process Arachidonate 12(S)-lipoxygenase Activity Keratinocyte Differentiation Terminal Web Metencephalon Development Establishment Of Blood-nerve Barrier
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