KRT6B and KRT24

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT6B	KRT24
Description		keratin 6B	keratin 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Ectoderm Development Keratinization Intermediate Filament Organization	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 30929738 31619474 31959851) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		30 interacting genes: GOLGA2 KDM1A KIFC3 KRT13 KRT15 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 LINC00839 NDC80 NUP62 OIP5 PDE4B SMARCB1 TEX11 TFIP11 TRIM54 TUBGCP4	36 interacting genes: AARD ABI2 ABI3 AIRIM AMOT BFSP2 C1orf216 CCDC146 CCHCR1 HGS KRT1 KRT2 KRT20 KRT3 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT78 KRT79 KRT8 KRT80 KRT81 ODAD3 PCM1 PRPH RCOR3 SGF29 SNAPIN TCHP TRIML2 TSGA10IP TXLNA
Entrez ID		3854	192666
HPRD ID		01012	09668
Ensembl ID		ENSG00000185479	ENSG00000167916
Uniprot IDs		P04259	Q2M2I5
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Cell Differentiation Cellular Developmental Process Extracellular Exosome Structural Constituent Of Cytoskeleton Developmental Process Cytosol Hair Follicle Morphogenesis Epidermis Development Gamma-tubulin Complex Hair Cycle Meiotic Spindle Assembly Hair Cycle Process Spindle Assembly Meiotic Spindle Organization Microtubule Binding Microtubule Nucleation Membraneless Organelle Assembly Intermediate Filament Polymerization Gamma-tubulin Binding Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Kinetochore Adaptor Activity Meiotic Gene Conversion Z Disc Chromosome Segregation	Intermediate Filament Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Structural Constituent Of Cytoskeleton Cytosol Intermediate Filament Cytoskeleton Extracellular Exosome Actin-based Cell Projection Cytoskeleton Protein Binding Cornified Envelope SCAR Complex Centriole Structural Molecule Activity Peptide Cross-linking Regulation Of Cell Projection Assembly Cell Projection Organization Desmosome
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