KRT33B and CNNM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT33B	CNNM3
Description		keratin 33B	cyclin and CBS domain divalent metal cation transport mediator 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Plasma Membrane Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Transmembrane Transporter Activity
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Cycle Intermediate Filament Organization	Monoatomic Ion Transport Magnesium Ion Homeostasis Transmembrane Transport
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Birth weight ( 31043758) Erectile dysfunction and prostate cancer treatment ( 20932654) Offspring birth weight ( 31043758)
Interacting Genes		61 interacting genes: ABI2 AIMP2 AQP1 ARFIP1 ATG9A C1orf216 CCDC24 CNNM3 COX5B CYSRT1 DES DTNB DUSP21 FASLG FRS3 GOLGA6L2 GSTP1 HAPLN2 HDAC4 HGS HOXA1 INCA1 KDM1A KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LMO4 MOS NUP54 NUP58 PATZ1 PPP1R18 RAB26 RAMAC RTP5 RUNX1T1 SCNM1 SGF29 SHC3 USP2 VPS37C	71 interacting genes: ACTN2 AGR2 AGR3 AKAP8L CALCOCO2 CARD10 CBY2 CCNDBP1 COG6 CYSRT1 EFEMP2 EXOSC8 FHL3 FHL5 GOLGA6L9 HNRNPK HOXA1 HSF2BP KHDRBS2 KHDRBS3 KPRP KRT31 KRT33B KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LZTS2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA P4HB PM20D2 PNMA1 PNMA2 PNMA3 PTP4A2 RBMX RBMY1F RBMY1J RBPMS RELA SRSF3 SSC4D TGM1 TNS2 TRIM27 UBE2G2 UBQLN2 USHBP1 VWC2 WWOX ZNF330 ZRANB1
Entrez ID		3884	26505
HPRD ID		04136	07419
Ensembl ID		ENSG00000131738	ENSG00000168763
Uniprot IDs		Q14525	Q8NE01
PDB IDs			5K22 5K23 5K25 5TSR 6DFD 6MN6 6WUR
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Keratin Filament Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Protein Binding Epidermis Development Intermediate Filament Cytoskeleton Extracellular Exosome Cornified Envelope Tissue Development Developmental Process Structural Constituent Of Cytoskeleton	Intermediate Filament Keratin Filament Identical Protein Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Protein Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Structural Constituent Of Skin Epidermis Nucleic Acid Binding Cytosol Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing
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