KIR3DL1 and CDK3

Number of citations of the paper that reports this interaction (PMID 11733001)
2

Data Source:
HPRD (in vivo, in vitro)

		KIR3DL1	CDK3
Gene Name		killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	cyclin-dependent kinase 3
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	HLA-B Specific Inhibitory MHC Class I Receptor Activity	Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Immune Response Signal Transduction Regulation Of Immune Response	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Cell Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CDK3 HLA-B RPS6KB1	18 interactors: APP CABLES1 CABLES2 CCNA2 CCNC CCNE1 CCNE2 CDC37 CDKN1A CDKN1B CDKN3 E2F1 E2F2 E2F3 KIR3DL1 NEDD4L PPARA RB1
Entrez ID		3811	1018
HPRD ID		09226	00446
Ensembl ID		ENSG00000167633	ENSG00000250506
Uniprot IDs		P43629 Q15702 Q5UCE2 Q8N6C9	Q00526
PDB IDs		3VH8	1LFN
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle G0 To G1 Transition Positive Regulation Of Skeletal Muscle Tissue Growth Protection From Natural Killer Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Skeletal Muscle Atrophy Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Response To Leucine Striated Muscle Atrophy Muscle Atrophy Skeletal Muscle Adaptation Regulation Of Dendritic Cell Differentiation Regulation Of T Cell Anergy Response To Bacterium Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Positive Regulation Of Translational Initiation Antigen Processing And Presentation Of Endogenous Antigen Mitotic Cell Cycle Process Response To Cytokine Response To Other Organism Detection Of Bacterium TOR Signaling Regulation Of Natural Killer Cell Mediated Cytotoxicity Response To Biotic Stimulus Mitotic Cell Cycle Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Skeletal Muscle Tissue Development Skeletal Muscle Contraction Detection Of Biotic Stimulus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Regulation Of Cell Cycle Response To Testosterone Negative Regulation Of Innate Immune Response Negative Regulation Of Insulin Receptor Signaling Pathway Protein Kinase B Signaling Regulation Of Smooth Muscle Cell Migration Response To Electrical Stimulus Musculoskeletal Movement Cell Cycle Process Long-term Memory Response To Glucagon Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of T Cell Mediated Cytotoxicity Regulation Of Insulin Receptor Signaling Pathway Regulation Of T Cell Mediated Cytotoxicity Regulation Of Glucose Import	Regulation Of Cell Cycle Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Process Cell Cycle Checkpoint Cell Division Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cellular Protein Metabolic Process Cell Cycle Process Regulation Of Mitotic Cell Cycle DNA-templated Transcription, Initiation Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Catalytic Activity Positive Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Lens Fiber Cell Apoptotic Process Notch Signaling Pathway Regulation Of Gene Expression Cell Cycle Arrest Positive Regulation Of Cellular Metabolic Process DNA Damage Checkpoint Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Macromolecule Biosynthetic Process Mitotic Cell Cycle Checkpoint Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Signal Transduction Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Fibroblast Proliferation Negative Regulation Of Cell Cycle Signaling Negative Regulation Of Mitotic Cell Cycle
Tagcloud ?		ab adaptor ap clathrin diminish diminished endocytosis endosomes engagement ig inhibitory internalization internalized itim killer kirs leaves maintaining mhc mu2 nk nonengaged prolonging readily recycling surface tyrosines undergoes	3h adenovirus augmented beta brdu cyclin d2 d3 dedifferentiation exit g0 g1 hypothesized incorporation inducing islets ki67 pancreatic prb quiescence quiescent rat recover regeneration replace staining thymidine transduced tunel
Tagcloud (Difference) ?		ab adaptor ap clathrin diminish diminished endocytosis endosomes engagement ig inhibitory internalization internalized itim killer kirs leaves maintaining mhc mu2 nk nonengaged prolonging readily recycling surface tyrosines undergoes	3h adenovirus augmented beta brdu cyclin d2 d3 dedifferentiation exit g0 g1 hypothesized incorporation inducing islets ki67 pancreatic prb quiescence quiescent rat recover regeneration replace staining thymidine transduced tunel
Tagcloud (Intersection) ?