NHLRC1 and AGL

Number of citations of the paper that reports this interaction (PMID 17908927)
22

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		NHLRC1	AGL
Gene Name		NHL repeat containing E3 ubiquitin protein ligase 1	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Cytosol Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Cytosol Inclusion Body Sarcoplasmic Reticulum Isoamylase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Glycogen Debranching Enzyme Activity 4-alpha-glucanotransferase Activity Amylo-alpha-1,6-glucosidase Activity Protein Binding Polysaccharide Binding Polyubiquitin Binding
	Biological Process	Protein Polyubiquitination Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glucose Metabolic Process Autophagy Pathogenesis Positive Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Small Molecule Metabolic Process	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Glucose Metabolic Process Response To Nutrient Pathogenesis Small Molecule Metabolic Process Response To Glucocorticoid
Pathways		Glucose metabolism Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates	Glucose metabolism Glycogen breakdown (glycogenolysis) Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS			White matter integrity (interaction) ( 23218918)
Protein-Protein Interactions		9 interactors: AGL EPM2A NNAT PPP1R3C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H	2 interactors: NHLRC1 PRKAB1
Entrez ID		378884	178
HPRD ID		06995	01984
Ensembl ID		ENSG00000187566	ENSG00000162688
Uniprot IDs		Q6VVB1	P35573
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Glycogen Biosynthetic Process Cellular Polysaccharide Biosynthetic Process Catabolic Process Polysaccharide Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Protein Catabolic Process Protein Ubiquitination Regulation Of DNA-templated Transcription In Response To Stress Protein Modification By Small Protein Conjugation Glycogen Metabolic Process Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Polysaccharide Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Macromolecule Catabolic Process Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Energy Reserve Metabolic Process Activation Of Innate Immune Response Glucose Metabolic Process Carbohydrate Biosynthetic Process Cellular Protein Modification Process Protein K11-linked Ubiquitination Positive Regulation Of Innate Immune Response Pathogenesis Hexose Metabolic Process Cellular Carbohydrate Metabolic Process Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Regulation Of Innate Immune Response Monosaccharide Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic Spindle Checkpoint Proteasomal Protein Catabolic Process Protein Monoubiquitination Negative Regulation Of Chromosome Segregation Proteolysis Spindle Checkpoint
Tagcloud ?		accepted apparently asses ataxia autosomal bodies cerebral characterizing codifying cortex dysregulation epm2a epm2b gabaergic glycogen imply lafora laforin malin myoclonic myoclonus neurodegeneration neurodevelopment neurotrophins operate p75ntr recessive seizures want	ag2 arrangements chance coordinating crystal crystalline crystallization crystallize cyclic diimide facile imidazol imidazole imidazolyl infinity interconversion isomerization isomers lattice oligomeric opening packing polymeric propyl pyromellitic rotation stacking thermogravimetric titration
Tagcloud (Difference) ?		accepted apparently asses ataxia autosomal bodies cerebral characterizing codifying cortex dysregulation epm2a epm2b gabaergic glycogen imply lafora laforin malin myoclonic myoclonus neurodegeneration neurodevelopment neurotrophins operate p75ntr recessive seizures want	ag2 arrangements chance coordinating crystal crystalline crystallization crystallize cyclic diimide facile imidazol imidazole imidazolyl infinity interconversion isomerization isomers lattice oligomeric opening packing polymeric propyl pyromellitic rotation stacking thermogravimetric titration
Tagcloud (Intersection) ?