KCNMB1 and KCNMA1

Number of citations of the paper that reports this interaction (PMID 8006036)
70

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		KCNMB1	KCNMA1
Gene Name		potassium channel subfamily M regulatory beta subunit 1	potassium channel, calcium activated large conductance subfamily M alpha, member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex	Plasma Membrane Caveola Voltage-gated Potassium Channel Complex Integral Component Of Membrane Apical Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Calcium-activated Potassium Channel Activity Potassium Channel Regulator Activity	Actin Binding Voltage-gated Potassium Channel Activity Protein Binding Calcium-activated Potassium Channel Activity Metal Ion Binding Large Conductance Calcium-activated Potassium Channel Activity
	Biological Process	Detection Of Calcium Ion Potassium Ion Transport Synaptic Transmission Blood Coagulation Potassium Ion Transmembrane Transport	Response To Hypoxia Potassium Ion Transport Response To Osmotic Stress Synaptic Transmission Blood Coagulation Cellular Potassium Ion Homeostasis Response To Carbon Monoxide Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Volume Response To Calcium Ion Micturition Smooth Muscle Contraction Involved In Micturition Potassium Ion Transmembrane Transport
Pathways		Ca2+ activated K+ channels Platelet homeostasis Potassium Channels Nitric oxide stimulates guanylate cyclase cGMP effects	Ca2+ activated K+ channels Platelet homeostasis Potassium Channels Nitric oxide stimulates guanylate cyclase cGMP effects
Drugs			Enflurane Chlorzoxazone Bendroflumethiazide Hydroflumethiazide Hydrochlorothiazide Cromoglicic acid Miconazole Diazoxide Halothane
Diseases
GWAS			Bone mineral density ( 22504420) Mortality among heart failure patients ( 20400778) Obesity ( 21708048)
Protein-Protein Interactions		4 interactors: CLCA1 COX1 EWSR1 KCNMA1	6 interactors: CACNA1H GGT1 HMOX2 KCNMB1 MAP1A PTK2
Entrez ID		3779	3778
HPRD ID		10358	15967
Ensembl ID			ENSG00000156113
Uniprot IDs		Q16558	B7ZMF5 D5MRH1 Q12791 Q59FH2 Q5SVJ8 Q6AI34 S4R453
PDB IDs			2K44 3MT5 3NAF
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Volume Smooth Muscle Contraction Involved In Micturition Response To Carbon Monoxide Response To Hypoxia Micturition Cellular Potassium Ion Homeostasis Urinary Bladder Smooth Muscle Contraction Potassium Ion Homeostasis Cyclooxygenase Pathway Prostaglandin Biosynthetic Process Prostaglandin Metabolic Process Cell Volume Homeostasis	Glutathione Catabolic Process Aldosterone Biosynthetic Process Cortisol Biosynthetic Process Heme Oxidation Netrin-activated Signaling Pathway Cysteine Biosynthetic Process Positive Regulation Of Acrosome Reaction Mineralocorticoid Biosynthetic Process Negative Regulation Of Synapse Assembly Cellular Response To Potassium Ion Signal Complex Assembly Heme Catabolic Process Cysteine Metabolic Process Response To Potassium Ion Glucocorticoid Biosynthetic Process Regulation Of Acrosome Reaction Response To Metal Ion Detection Of Calcium Ion
Tagcloud ?		1alpha address beta1 bp chip coactivator cytosolic deacetylase discrete elucidate herein hif highlighting hpasmc hres hypoxia hypoxic located modulating mutagenesis plasmid potassium potentiated shrna smc speculate tone trichostatin whereby	10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating
Tagcloud (Difference) ?		1alpha address beta1 bp chip coactivator cytosolic deacetylase discrete elucidate herein hif highlighting hpasmc hres hypoxia hypoxic located modulating mutagenesis plasmid potassium potentiated shrna smc speculate tone trichostatin whereby	10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating
Tagcloud (Intersection) ?