KCNMA1 and KCNMB1

Number of citations of the paper that reports this interaction (PMID 8006036)
70

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		KCNMA1	KCNMB1
Gene Name		potassium channel, calcium activated large conductance subfamily M alpha, member 1	potassium channel subfamily M regulatory beta subunit 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Caveola Voltage-gated Potassium Channel Complex Integral Component Of Membrane Apical Plasma Membrane Extracellular Vesicular Exosome	Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Actin Binding Voltage-gated Potassium Channel Activity Protein Binding Calcium-activated Potassium Channel Activity Metal Ion Binding Large Conductance Calcium-activated Potassium Channel Activity	Calcium-activated Potassium Channel Activity Potassium Channel Regulator Activity
	Biological Process	Response To Hypoxia Potassium Ion Transport Response To Osmotic Stress Synaptic Transmission Blood Coagulation Cellular Potassium Ion Homeostasis Response To Carbon Monoxide Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Volume Response To Calcium Ion Micturition Smooth Muscle Contraction Involved In Micturition Potassium Ion Transmembrane Transport	Detection Of Calcium Ion Potassium Ion Transport Synaptic Transmission Blood Coagulation Potassium Ion Transmembrane Transport
Pathways		Ca2+ activated K+ channels Platelet homeostasis Potassium Channels Nitric oxide stimulates guanylate cyclase cGMP effects	Ca2+ activated K+ channels Platelet homeostasis Potassium Channels Nitric oxide stimulates guanylate cyclase cGMP effects
Drugs		Enflurane Chlorzoxazone Bendroflumethiazide Hydroflumethiazide Hydrochlorothiazide Cromoglicic acid Miconazole Diazoxide Halothane
Diseases
GWAS		Bone mineral density ( 22504420) Mortality among heart failure patients ( 20400778) Obesity ( 21708048)
Protein-Protein Interactions		6 interactors: CACNA1H GGT1 HMOX2 KCNMB1 MAP1A PTK2	4 interactors: CLCA1 COX1 EWSR1 KCNMA1
Entrez ID		3778	3779
HPRD ID		15967	10358
Ensembl ID		ENSG00000156113
Uniprot IDs		B7ZMF5 D5MRH1 Q12791 Q59FH2 Q5SVJ8 Q6AI34 S4R453	Q16558
PDB IDs		2K44 3MT5 3NAF
Enriched GO Terms of Interacting Partners?		Glutathione Catabolic Process Aldosterone Biosynthetic Process Cortisol Biosynthetic Process Heme Oxidation Netrin-activated Signaling Pathway Cysteine Biosynthetic Process Positive Regulation Of Acrosome Reaction Mineralocorticoid Biosynthetic Process Negative Regulation Of Synapse Assembly Cellular Response To Potassium Ion Signal Complex Assembly Heme Catabolic Process Cysteine Metabolic Process Response To Potassium Ion Glucocorticoid Biosynthetic Process Regulation Of Acrosome Reaction Response To Metal Ion Detection Of Calcium Ion	Negative Regulation Of Cell Volume Smooth Muscle Contraction Involved In Micturition Response To Carbon Monoxide Response To Hypoxia Micturition Cellular Potassium Ion Homeostasis Urinary Bladder Smooth Muscle Contraction Potassium Ion Homeostasis Cyclooxygenase Pathway Prostaglandin Biosynthetic Process Prostaglandin Metabolic Process Cell Volume Homeostasis
Tagcloud ?		10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating	1alpha address beta1 bp chip coactivator cytosolic deacetylase discrete elucidate herein hif highlighting hpasmc hres hypoxia hypoxic located modulating mutagenesis plasmid potassium potentiated shrna smc speculate tone trichostatin whereby
Tagcloud (Difference) ?		10ng agreed atr bard1 belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating	1alpha address beta1 bp chip coactivator cytosolic deacetylase discrete elucidate herein hif highlighting hpasmc hres hypoxia hypoxic located modulating mutagenesis plasmid potassium potentiated shrna smc speculate tone trichostatin whereby
Tagcloud (Intersection) ?