IMPA2 and IMPA1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IMPA2	IMPA1
Gene Name		inositol(myo)-1(or 4)-monophosphatase 2	inositol(myo)-1(or 4)-monophosphatase 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Inositol Monophosphate 1-phosphatase Activity Protein Homodimerization Activity Metal Ion Binding Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity	Magnesium Ion Binding Inositol Monophosphate 1-phosphatase Activity Manganese Ion Binding Lithium Ion Binding Identical Protein Binding Protein Homodimerization Activity Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity
	Biological Process	Inositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation Inositol Phosphate Dephosphorylation	Inositol Biosynthetic Process Phosphatidylinositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation Inositol Phosphate Dephosphorylation
Pathways		Synthesis of IP2, IP, and Ins in the cytosol Inositol phosphate metabolism	Synthesis of IP2, IP, and Ins in the cytosol Inositol phosphate metabolism
Drugs		Lithium	Lithium L-Myo-Inositol-1-Phosphate
Diseases
GWAS		Stroke ( 17434096)	Ovarian cancer ( 23535730)
Protein-Protein Interactions		4 interactors: HERPUD1 IMPA1 TNFRSF14 UBA3	4 interactors: CALB1 IMPA2 NXF1 S100B
Entrez ID		3613	3612
HPRD ID		09329	03641
Ensembl ID		ENSG00000141401	ENSG00000133731
Uniprot IDs		O14732	P29218
PDB IDs		2CZH 2CZI 2CZK 2DDK 2FVZ	1AWB 1IMA 1IMB 1IMC 1IMD 1IME 1IMF 2HHM 4AS4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Endomitotic Cell Cycle Positive Regulation Of Cytokine Secretion Involved In Immune Response	Memory Metanephric Connecting Tubule Development Regulation Of Synaptic Plasticity Negative Regulation Of Skeletal Muscle Cell Differentiation Metanephric Part Of Ureteric Bud Development Learning Or Memory Cognition Metanephric Distal Convoluted Tubule Development Regulation Of Synaptic Transmission Metanephric Distal Tubule Development Inositol Biosynthetic Process Poly(A)+ MRNA Export From Nucleus Response To Methylmercury Metanephric Collecting Duct Development Distal Tubule Development Inositol Phosphate Dephosphorylation Phosphorylated Carbohydrate Dephosphorylation Single-organism Behavior Collecting Duct Development Short-term Memory Metanephric Nephron Tubule Development Regulation Of Skeletal Muscle Cell Differentiation Negative Regulation Of Skeletal Muscle Tissue Development Behavior Inositol Metabolic Process Retina Layer Formation Metanephric Epithelium Development Metanephros Morphogenesis Astrocyte Differentiation Long-term Memory Negative Regulation Of Striated Muscle Tissue Development Long-term Synaptic Potentiation Inositol Phosphate Metabolic Process Negative Regulation Of Muscle Organ Development Alcohol Catabolic Process Neural Retina Development Retina Morphogenesis In Camera-type Eye Regulation Of Neuronal Synaptic Plasticity MRNA Export From Nucleus Regulation Of Skeletal Muscle Tissue Development
Tagcloud ?		accomplices counterbalance dao daoa dictate dpysl2 dtnbp1 famine grin1 grin2b grm3 grm4 hypomyelination il1b il1rn metabotropic ncam1 nd4 ndufv2 nos1 nos1ap nurture oligodendrocyte pdlim5 pik3c3 pip5k2a reconcile rgs4 ywhah
Tagcloud (Difference) ?		accomplices counterbalance dao daoa dictate dpysl2 dtnbp1 famine grin1 grin2b grm3 grm4 hypomyelination il1b il1rn metabotropic ncam1 nd4 ndufv2 nos1 nos1ap nurture oligodendrocyte pdlim5 pik3c3 pip5k2a reconcile rgs4 ywhah
Tagcloud (Intersection) ?