IL16 and KCNJ1

Number of citations of the paper that reports this interaction (PMID 10479680)
9

Data Source:
BioGRID (two hybrid)

		IL16	KCNJ1
Gene Name		interleukin 16	potassium channel, inwardly rectifying subfamily J, member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Plasma Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Cytokine Activity	Inward Rectifier Potassium Channel Activity ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding ATP-activated Inward Rectifier Potassium Channel Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Immune Response Viral Process Leukocyte Chemotaxis Induction Of Positive Chemotaxis	Kidney Development Tissue Homeostasis Potassium Ion Transport Synaptic Transmission Excretion Post-embryonic Development Potassium Ion Import Regulation Of Ion Transmembrane Transport Renal Sodium Ion Absorption Cardiovascular System Development Regulation Of G-protein Activated Inward Rectifier Potassium Channel Activity
Pathways			Inwardly rectifying K+ channels Potassium transport channels Potassium Channels
Drugs			Bethanidine Glimepiride Minoxidil Acetohexamide Tolazamide Glyburide Tolbutamide Glycodiazine Agmatine
Diseases
GWAS		Inattentive symptoms ( 18821565)
Protein-Protein Interactions		28 interactors: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ1 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A PPP1R12A PPP1R12B PPP1R12C SSSCA1 SUV39H1 USHBP1	8 interactors: GOLGA3 IL16 PRKCD SGK1 SH3RF1 SLC9A3R1 SLC9A3R2 UBC
Entrez ID		3603	3758
HPRD ID		04329	08981
Ensembl ID		ENSG00000172349	ENSG00000151704
Uniprot IDs		Q14005 Q9UME6	A8K432 P48048
PDB IDs		1I16 1X6D
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Potassium Ion Transmembrane Transport Potassium Ion Transport Potassium Ion Import Cell-cell Signaling Cation Transmembrane Transport Signaling Cell Communication Ion Transmembrane Transport Metal Ion Transport Regulation Of Ion Transmembrane Transport Cation Transport Transmembrane Transport Ion Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Ion Transport Monovalent Inorganic Cation Transport Regulation Of Membrane Potential Regulation Of Cellular Process Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Regulation Of Sensory Perception Of Pain Startle Response Directional Locomotion Protein Homooligomerization Membrane Depolarization Negative Regulation Of Protein Catabolic Process Neuromuscular Process Regulation Of Resting Membrane Potential Regulation Of Neurological System Process Regulation Of Protein Catabolic Process Cell Cycle Regulation Of Excitatory Postsynaptic Membrane Potential Mitotic Cell Cycle Process Regulation Of Postsynaptic Membrane Potential Response To Wounding Protein Complex Assembly Cell Cycle Process Protein Oligomerization Negative Regulation Of Cell Cycle Potassium Ion Homeostasis Mitotic Cell Cycle Negative Regulation Of Chromosome Organization Locomotion G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Process Response To External Stimulus	Renal Sodium Ion Transport Renal Absorption Negative Regulation Of Signal Transduction Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Signaling Regulation Of MAPK Cascade Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Intracellular Signal Transduction Positive Regulation Of Transporter Activity Apoptotic Process Programmed Cell Death Cell Death Death Negative Regulation Of Intracellular Signal Transduction Renal Phosphate Ion Absorption Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Catalytic Activity Renal System Process Regulation Of Phosphorylation Negative Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Phospholipid Catabolic Process Glutathione Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cell Death Regulation Of Signal Transduction Interleukin-10 Production Regulation Of Locomotion Negative Regulation Of MAPK Cascade Epidermal Growth Factor Receptor Signaling Pathway Renal Sodium Ion Absorption Negative Regulation Of Filopodium Assembly Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Signaling Regulation Of Protein Kinase Activity Interleukin-12 Production Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Catalytic Activity Response To Fibroblast Growth Factor Regulation Of Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway Cellular Phosphate Ion Homeostasis Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Sodium:proton Antiporter Activity
Tagcloud ?			2cl a198t ante antenatal ascending ba2 bartter cdnas cos cotransport currents d108h henle infrequently inwardly kir mg2 p110l potassium reabsorption rectifying romk romk1 salt talh v315g v72e wasting wildtype
Tagcloud (Difference) ?			2cl a198t ante antenatal ascending ba2 bartter cdnas cos cotransport currents d108h henle infrequently inwardly kir mg2 p110l potassium reabsorption rectifying romk romk1 salt talh v315g v72e wasting wildtype
Tagcloud (Intersection) ?