LCE3A and VWC2L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCE3A	VWC2L
Description		late cornified envelope 3A	von Willebrand factor C domain containing 2 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Region Extracellular Space AMPA Glutamate Receptor Complex Synapse
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Epidermis Development Keratinization Killing Of Cells Of Another Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Neuron Differentiation
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23727859) Inflammatory skin disease ( 25574825) Psoriasis ( 19169255) Psoriasis vulgaris ( 26626624)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Degraded stimulus continuous performance test score ( 31596458) Dietary fat liking ( 32516399) Household income (MTAG) ( 31844048) Neuroticism ( 29255261) PR interval ( 23534349)
Interacting Genes		74 interacting genes: ADAMTSL4 ALPP CHIC2 CRCT1 CYSRT1 EFEMP1 EFEMP2 FBLN1 HOXA1 KPRP KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2B LCE2C LCE2D LCE3B LCE4A MACO1 MDFI NBPF19 NOTCH2NLA OIT3 PCSK5 PLA2G10 PLSCR2 RGS17 RGS20 SMCP SPRY1 SPRY3 TGFB1 TGM1 TRIM42 TSPAN4 VASN VWC2 VWC2L	29 interacting genes: C17orf50 C22orf39 CD36 CEMP1 CRCT1 CXCL5 CYSRT1 DEFB112 FBXO34 FHL3 HOXA1 KRTAP10-8 KRTAP11-1 KRTAP19-2 LCE1A LCE1C LCE3A LCE3D LCE5A MEOX2 NR4A3 OTX1 PPARA RIPK4 SPATA3 TRIM42 TYRO3 YPEL3 ZNF20
Entrez ID		353142	402117
HPRD ID		13973	19160
Ensembl ID		ENSG00000185962	ENSG00000174453
Uniprot IDs		Q5TA76	B2RUY7 B7ZW27
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Hair Cycle Protein Binding Cytosol Tissue Development Elastic Fiber Identical Protein Binding Interstitial Matrix	Epidermis Development Keratinization Tissue Development
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