VWC2L and DEFB112

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VWC2L	DEFB112
Description		von Willebrand factor C domain containing 2 like	defensin beta 112
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space AMPA Glutamate Receptor Complex Synapse	Extracellular Region
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Neuron Differentiation	Defense Response Defense Response To Bacterium Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Degraded stimulus continuous performance test score ( 31596458) Dietary fat liking ( 32516399) Household income (MTAG) ( 31844048) Neuroticism ( 29255261) PR interval ( 23534349)	Body mass index ( 25673413) Breast size ( 22747683) Overweight status ( 25133637) Western dietary pattern ( 28644415)
Interacting Genes		29 interacting genes: C17orf50 C22orf39 CD36 CEMP1 CRCT1 CXCL5 CYSRT1 DEFB112 FBXO34 FHL3 HOXA1 KRTAP10-8 KRTAP11-1 KRTAP19-2 LCE1A LCE1C LCE3A LCE3D LCE5A MEOX2 NR4A3 OTX1 PPARA RIPK4 SPATA3 TRIM42 TYRO3 YPEL3 ZNF20	3 interacting genes: HSF2BP KRTAP10-1 VWC2L
Entrez ID		402117	245915
HPRD ID		19160	18757
Ensembl ID		ENSG00000174453	ENSG00000180872
Uniprot IDs		B2RUY7 B7ZW27	A0A494C1K0
PDB IDs
Enriched GO Terms of Interacting Partners?		Epidermis Development Keratinization Tissue Development
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